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D26202
3,5-Diamino-1,2,4-Triazol
98%
Synonym(e):
Guanazol
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About This Item
Empirische Formel (Hill-System):
C2H5N5
CAS-Nummer:
Molekulargewicht:
99.09
Beilstein:
112467
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22
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Qualitätsniveau
Assay
98%
Form
solid
mp (Schmelzpunkt)
202-205 °C (lit.)
SMILES String
Nc1n[nH]c(N)n1
InChI
1S/C2H5N5/c3-1-5-2(4)7-6-1/h(H5,3,4,5,6,7)
InChIKey
PKWIYNIDEDLDCJ-UHFFFAOYSA-N
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Anwendung
Inhibitor of DNA synthesis.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Aquatic Chronic 2 - Repr. 2 - STOT RE 2
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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L Guennoun et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 78(1), 347-353 (2010-11-30)
The 3,5-diamino-1,2,4-triazole (guanazole) was investigated by vibrational spectroscopy and quantum methods. The solid phase FT-IR and FT-Raman spectra were recorded in the region 4000-400 cm(-1) and 3600-50 cm(-1) respectively, and the band assignments were supported by deuteration effects. The results
W Suter et al.
Mutation research, 231(2), 251-264 (1990-08-01)
Guanazole and aphidicolin were chosen as candidates in the search for a selective, non-genotoxic inhibitor of DNA replication which could be used instead of hydroxyurea to measure DNA repair synthesis in rat hepatocyte primary cultures by liquid scintillation counting. The
V M Kolb et al.
Journal of molecular evolution, 38, 549-557 (1994-01-01)
Urazole is a five-membered heterocyclic compound which is isosteric with uracil's hydrogen-bonding segment. Urazole reacts spontaneoulsy with ribose (and other aldoses) to give a mixture of four ribosides: alpha and beta pyranosides and furanosides. This reaction occurs in aqueous solution
A A Alhaider et al.
Journal of pharmaceutical sciences, 71(1), 89-94 (1982-01-01)
A series of guanazole prodrugs, which are less water soluble than the parent compound and have relatively higher molecular weights, was recently synthesized, and their antineoplastic activities were measured in vitro. In present work, the ionization constants and partition coefficients
A Sato et al.
Advances in enzyme regulation, 22, 231-241 (1984-01-01)
The data presented here show that while the non-heme iron subunit of ribonucleotide reductase is inhibited by IMPY, hydroxyurea and MAIQ, the mechanism of inhibition by hydroxyurea and IMPY is distinct from that for MAIQ. This difference in mechanisms is
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