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Merck

915092

Sigma-Aldrich

Poly(3-hydroxybutyric acid)

natural origin, average Mn ~500,000

Synonym(e):

P3HB, PHA, PHB, Polyhydroxybutyrate

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About This Item

Lineare Formel:
(C4H6O2)nH2O
CAS-Nummer:
UNSPSC-Code:
12352106
NACRES:
NA.25

Qualitätsniveau

Form

powder

Mol-Gew.

average Mn ~500,000

Farbe

white to off-white

Lagertemp.

2-8°C

Anwendung

Poly(3-hydroxybutyric acid) (PHB) is a common polyhydroxyalkanoate (PHA), it has been widely used for food packaging, medical implants, biodegradable sutures and drug delivery systems due to its biocompatible and biodegradable properties. PHB has been investigated as drug delivery micro- and nano-carriers.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Senthilkumar Pachiyappan et al.
IET nanobiotechnology, 13(4), 416-427 (2019-06-07)
In this study, polyhydroxybutyrate (PHB) nanoparticles were synthesised following nanoprecipitation method having different solvents and surfactant (Tween 80) concentrations. In this study, PHB nanoparticles were encapsulated with curcumin and subjected for sustained curcumin delivery. Both the curcumin loaded and unloaded
Sumeet Kapoor et al.
International journal of pharmaceutics, 511(2), 876-889 (2016-08-06)
Faster biodegradation, immunogenicity and lack of cell penetrative capabilities are hurdles in development of peptidyl drugs for cancer therapy. Polymeric carriers can be used to overcome these problems. The present study is focused on the use of polyhydroxybutyrate as a
K Juni et al.
Critical reviews in therapeutic drug carrier systems, 3(3), 209-232 (1987-01-01)
Poly(hydroxy acids) so far have been examined for use in drug delivery in limited number, while the advantageous use of the polymers has been recognized due to their biodegradability and biocompatibility. Homo- and copolymers of lactic acid and glycolic acid

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