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Merck

913286

Sigma-Aldrich

Methoxypolyethylene epoxide

PEG average Mn 750

Synonym(e):

Epoxide PEG, mPEG-epoxide

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About This Item

Lineare Formel:
C3H5O2(C2H4O)nCH3
UNSPSC-Code:
43211915
NACRES:
NA.23

Form

semisolid

Mol-Gew.

PEG average Mn 750
average Mn 750 (by NMR)

Farbe

white to off-white

Ω-Ende

(epoxide)

α-Ende

methoxy

Polymerarchitektur

shape: linear
functionality: monofunctional

Lagertemp.

2-8°C

Anwendung

Epoxide functionalized PEG can be covalently bonded to polymers and biopolymers by epoxide ring-opening reactions. As a surface coating, PEGylated surfaces prevent cell adhesion by entropically driven steric repulsion. For drug delivery, PEGylation increases the hydrophilicity of the drug carrier.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Rajesh K Kainthan et al.
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There is a huge clinical demand for Human Serum Albumin (HSA), with a world market of approximately $1.5B/year. Concern over prion and viral transmission in the blood supply has led to a need for safer substitutes and offers the opportunity
Rajesh Kumar Kainthan et al.
Biomaterials, 27(31), 5377-5390 (2006-07-21)
A novel class of hyperbranched polymers based on polyglycerol (PG) and poly(ethylene glycol) (PEG) are synthesized by multibranching anionic ring opening polymerization. Multivalent cationic sites are added to these polymers by a post-amination and quarternization reactions. Blood compatibility studies using
Jameel Ahmad Khan et al.
Biomacromolecules, 7(5), 1386-1388 (2006-05-09)
Recent advances in understanding biological systems have proven that RNA is not merely the carrier of genetic information, but also a key molecule in regulation of gene expression and other crucial metabolic processes. Therefore, it is being considered as an
Mohamed H Ramadan et al.
Langmuir : the ACS journal of surfaces and colloids, 30(25), 7485-7495 (2014-06-04)
We report a thermoresponsive chemical modification strategy of hyaluronic acid (HA) for coating onto a broad range of biomaterials without relying on chemical functionalization of the surface. Poly(di(ethylene glycol) methyl ether methacrylate) (PMEO2MA), a polymer with a lower critical solution
Rajesh Kumar Kainthan et al.
Biomacromolecules, 9(3), 886-895 (2008-02-06)
This paper discusses the binding and release properties of hydrophobically modified hyperbranched polyglycerol-polyethylene glycol copolymers that were originally developed as human serum albumin (HSA) substitutes. Their unimolecular micellar nature in aqueous solution has been proven by size measurements and other

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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