904643

Thiol functionalized gelatin

• Synonym(e): Functionalized gelatin, Gelatin thiol, Gelatin-SH• Gel-SH, SH functionalized gelatin, Thiol functionalized gelatin, Thiol gelatin, Thiolated gelatin
• UNSPSC-Code: 12352105
• NACRES: NA.23

Eigenschaften

• Beschreibung: NMR: Conforms to structure; Thiol content 150-350 μmol/g
• Assay: 150-350 μmol/g (Free Thiol Concentration by UVVI, UV-vis)
• Form: powder
• Farbe: white to pale yellow
• Lagertemp.: −20°C

Beschreibung

Anwendung

Gelatin has received significant attention in the biomedical field due to its inherent bioactivity. Functionalized gelatin can be cross-linked with the formation of covalent bonds into highly crosslinked structures, such as hydrogels. Recent literature suggests that radical-mediated polymerized hydrogels may not be ideal for cell and protein encapsulation due to radical-mediated damage, hindered molecular transport, or altered cell-cell/cell-material interactions. Thiol-modified gelatin can be used to form hydrogels with multifunctional norbornene or allyl crosslinkers via thiol-ene click or Michael-addition reactions.

To improve solubility in water, heat to 40°C and stir for 10-15 minutes.

Vorsicht

Material should be handled under nitrogen - air/oxygen & moisture are to be avoided.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable