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Resomer® RG 505, Poly(D,L-lactide-co-glycolide)
ester terminated, Mw 54,000-69,000
Synonym(e):
PLGA
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About This Item
Empfohlene Produkte
Qualitätsniveau
Form
amorphous
Zufuhrverhältnis
lactide:glycolide 50:50
Mol-Gew.
Mw 54,000-69,000
Zeitrahmen für den Abbau
<3 months
Viskosität
0.61-0.74 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)
Übergangstemp.
Tg 48-52 °C
Lagertemp.
2-8°C
InChI
1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2
InChIKey
LCSKNASZPVZHEG-UHFFFAOYSA-N
Verwandte Kategorien
Allgemeine Beschreibung
Poly(lactide-co-glycolide)(PLGA) is a biodegradable polymer used in the preparation of polymericmicrospheres. These polymers degrade in vivo by hydrolysis of their esterbackbone into non-toxic products, which are excreted by the kidneys oreliminated as CO2 and water through biochemical pathways. PLGAmicrospheres have been widely used to encapsulate drug molecules and have beenused as long-acting, sustained-release pharmaceutical formulations.
Anwendung
Poly(lactide-co-glycolide)(PLGA) can be used to fabricate sustained-release drug delivery systems, for example, it can be used to encapsulate the anti-inflammatory lipophilic drug atorvastatin.
Rechtliche Hinweise
Product of Evonik
RESOMER is a registered trademark of Evonik Rohm GmbH
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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