735353

Lithium-2,2,6,6-Tetramethylpiperidid Lithiumderivat

95%

• Synonym(e): 2,2,6,6-Tetramethylpiperidine lithium salt (1:1), LTMP
• Empirische Formel (Hill-System): C₉H₁₈LiN
• CAS-Nummer: 38227-87-1
• Molekulargewicht: 147.19
• MDL-Nummer: MFCD00015910
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 329764934
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 95%
• Form: solid
• SMILES String: [Li]N1C(C)(C)CCCC1(C)C
• InChI: 1S/C9H18N.Li/c1-8(2)6-5-7-9(3,4)10-8;/h5-7H2,1-4H3;/q-1;+1
• InChIKey: ANYSGBYRTLOUPO-UHFFFAOYSA-N

Beschreibung

Anwendung

Lithium 2,2,6,6-tetramethylpiperidide is a strong base and can be used:

• For the synthesis of enamines from terminal epoxides through trans-α-lithiated epoxide as an intermediate.
• For ortholithiation of arenes such as 1,3-bis(trifluoromethyl)benzene, 4,4-dimethyl-2-phenyl-2-oxazoline, 1,4-bis(trifluoromethyl)benzene and 1,3-dimethoxybenzene.
• In combination with Lewis donor ligand, N,N,N′,N′-tetramethylethylenediamine (TMEDA) for deprotonative metalation of methoxy-substituted arenes.{21]

Sicherheitshinweise

• Piktogramme: GHS02,GHS05
• Signalwort: Danger
• H-Sätze: H261,H314
• P-Sätze: P231 + P232 - P280 - P305 + P351 + P338 - P310 - P422
• Gefahreneinstufungen: Skin Corr. 1B - Water-react 2
• Lagerklassenschlüssel: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable