474789

(S)-(−)-Glycidol

97%, optical purity ee: 98% (GLC)

• Synonym(e): (S)-(−)-2,3-Epoxy-1-propanol, (S)-(−)-Oxiran-2-methanol
• Empirische Formel (Hill-System): C₃H₆O₂
• CAS-Nummer: 60456-23-7
• Molekulargewicht: 74.08
• Beilstein: 79783
• MDL-Nummer: MFCD00074874
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24871051
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Optische Aktivität: [α]20/D −15°, neat
• Optische Reinheit: ee: 98% (GLC)
• Brechungsindex: n20/D 1.433 (lit.)
• bp: 66-67 °C/19 mmHg (lit.)
• Dichte: 1.116 g/mL at 20 °C (lit.)
• Funktionelle Gruppe: ether; hydroxyl
• Lagertemp.: −20°C
• SMILES String: OC[C@H]1CO1
• InChI: 1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2/t3-/m0/s1
• InChIKey: CTKINSOISVBQLD-VKHMYHEASA-N

Beschreibung

Allgemeine Beschreibung

Glycidol or 2,3-epoxy-1-propanol is a highly reactive epoxy derivative, which is generally used as a monomer in the preparation of many polymers like polyesters, polycarbonates, polyurethanes, and polyamides. It is also used in the preparation of detergents, rubbers, perfumes, fabric dyes, varnishes, cosmetics, and paints.

Anwendung

Employed in the synthesis of chiral (E)-allylic alcohol side-chains for introduction into prostacyclin and prostaglandin frameworks by cross-metathesis.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H302 + H312,H315,H319,H330,H335,H341,H350,H360F
• P-Sätze: P202 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 2 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 161.6 °F
• Flammpunkt (°C): 72 °C
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter