468495

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyaninperchlorat

97%

• Synonym(e): DiIC₁₈(3)
• Empirische Formel (Hill-System): C₅₉H₉₇ClN₂O₄
• CAS-Nummer: 41085-99-8
• Molekulargewicht: 933.87
• Beilstein: 8251870
• MDL-Nummer: MFCD00142354
• UNSPSC-Code: 12171500
• PubChem Substanz-ID: 24870519
• NACRES: NA.47

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Form: crystalline
• Zusammensetzung: Carbon: 73.2-78.5%; ; Nitrogen: 2.7-3.3%
• Methode(n): titration: suitable
• Farbe: dark purple
• mp (Schmelzpunkt): 68 °C (dec.) (lit.)
• λmax: 549 nm
• ε (Extinktionskoeffizient): ≥10000 at 276-282 nm in methanol at 0.01 g/L; ≥130000 at 546-552 nm in methanol at 0.01 g/L; ≥70000 at 514-520 nm in methanol at 0.01 g/L
• Anwendung(en): diagnostic assay manufacturing; hematology; histology
• Lagertemp.: 2-8°C
• SMILES String: [O-]Cl(=O)(=O)=O.CCCCCCCCCCCCCCCCCCN1c2ccccc2C(C)(C)/C1=C\C=C\C3=[N+](CCCCCCCCCCCCCCCCCC)c4ccccc4C3(C)C
• InChI: 1S/C59H97N2.ClHO4/c1-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-41-50-60-54-46-39-37-44-52(54)58(3,4)56(60)48-43-49-57-59(5,6)53-45-38-40-47-55(53)61(57)51-42-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-2;2-1(3,4)5/h37-40,43-49H,7-36,41-42,50-51H2,1-6H3;(H,2,3,4,5)/q+1;/p-1
• InChIKey: JVXZRNYCRFIEGV-UHFFFAOYSA-M

Beschreibung

Allgemeine Beschreibung

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate is also called as Dil. It can be used to study HCV (Hepatitis C virus) cell interactions in the HCV entry process. It is used to label oxidized LDL (low-density lipoprotein) to quantify the uptake of DiI-oxLDL in human endothelial cells.

Anwendung

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate has been used in cytoskeletal staining, nuclear staining, retrograde labeling, counting of motor neurons and labelling of the retinal ganglion cell axons.

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate has been used in fluorescent labelling of mesenchymal stem cells (MSCs) and cerebral cortex. It has also been used in electromyogram (EMG) to determine awake and anesthetized states in mice.

Biochem./physiol. Wirkung

Lipophiler Carbocyanin-Farbstoff, der primär für optische Aufnahmen der Membranspannung und für Studien der Membranfluidität eingesetzt wird. Retrograde Färbung von Neuronen; bietet intensive, langanhaltende Farbe von lebenden Neuronen in vivo und in vitro.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)