460923

Propargylchlorformiat

96%

• Synonym(e): (Prop-2-ynyloxy)carbonyl chloride, 2-Propyn-1-yl carbonochloridate, 2-Propynyl chloroformate, Prop-2-yn-1-yl carbonochloridate, Propargyloxycarbonyl chloride
• Lineare Formel: HC≡CCH₂OCOCl
• CAS-Nummer: 35718-08-2
• Molekulargewicht: 118.52
• Beilstein: 1745399
• MDL-Nummer: MFCD00270127
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24869771
• NACRES: NA.22

Eigenschaften

• Dampfdruck: 0.65 psi ( 20 °C)
• Qualitätsniveau: 100
• Assay: 96%
• Eignung der Reaktion: reaction type: click chemistry
• Brechungsindex: n20/D 1.435 (lit.)
• bp: 118-122 °C (lit.)
• Dichte: 1.215 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: chloro
• Lagertemp.: 2-8°C
• SMILES String: ClC(=O)OCC#C
• InChI: 1S/C4H3ClO2/c1-2-3-7-4(5)6/h1H,3H2
• InChIKey: RAMTXCRMKBFPRG-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Propargyl chloroformate is a propargyl ester. It serves as a protecting group for the hydroxy and amino functional group. Rates of solvolysis of propargyl chloroformate has been analyzed in various solvents of widely varying nucleophilicity and ionizing power values using the extended Grunwald-Winstein equation.

Anwendung

Propargyl chloroformate may be used for the preparation of the following:

• binaphthol-diacetylene derivatives
• propargyl pentafluorophenyl carbonate
• N-Poc protected amino acids (Poc = propargyloxycarbonyl)

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS05
• Signalwort: Danger
• H-Sätze: H226,H302,H311 + H331,H314
• P-Sätze: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Flam. Liq. 3 - Skin Corr. 1B
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 86.0 °F - closed cup
• Flammpunkt (°C): 30 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter