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Merck

261394

Sigma-Aldrich

N,N-Dimethylharnstoff

99%

Synonym(e):

N,N-Dimethylurea

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About This Item

Lineare Formel:
(CH3)2NCONH2
CAS-Nummer:
Molekulargewicht:
88.11
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22

Qualitätsniveau

Assay

99%

Form

solid

mp (Schmelzpunkt)

178-183 °C (lit.)

Löslichkeit

water: soluble 5%, clear, colorless

Funktionelle Gruppe

amine

SMILES String

CN(C)C(N)=O

InChI

1S/C3H8N2O/c1-5(2)3(4)6/h1-2H3,(H2,4,6)

InChIKey

YBBLOADPFWKNGS-UHFFFAOYSA-N

Angaben zum Gen

human ... EPHX2(2053)
mouse ... Ephx2(13850)

Allgemeine Beschreibung

Nonlinear optical properties of 1,1-dimethylurea (N,N′ dimethylurea), have been evaluated through second-harmonic generation.

Anwendung

1,1-Dimethylurea (N,N-dimethylurea) has been used in the Dowex-50W ion exchange resin-promoted synthesis of N,N′-disubstituted-4-aryl-3,4-dihydropyrimidinones.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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K Yamada et al.
Acta endocrinologica, 128(4), 379-384 (1993-04-01)
We investigated the effect of free radical scavengers on the actions of cytokines on islet cells. Interferon-gamma and tumor necrosis factor-alpha reduced the nicotinamide adenine dinucleotide content of mouse islet cells; the combination of interferon-gamma (4 x 10(5) U/l) and
S Sandler et al.
Endocrinology, 124(3), 1492-1501 (1989-03-01)
This study aimed at a more detailed characterization of the mechanisms by which interleukin 1 (IL-1) inhibits insulin secretion. For this purpose, isolated rat pancreatic islets were kept in tissue culture for 5 days in medium RPMI 1640 plus 10%
Wanli Lu et al.
Chemistry & biology, 18(4), 425-431 (2011-04-26)
Pactamycin, one of the most densely functionalized aminocyclitol antibiotics, has pronounced antibacterial, antitumor, antiviral, and antiplasmodial activities, but its development as a clinical drug was hampered by its broad cytotoxicity. Efforts to modulate the biological activity by structural modifications using
J W McDonald et al.
The American review of respiratory disease, 143(4 Pt 1), 806-809 (1991-04-01)
Eugenol, an extract of cloves, has been associated with pulmonary edema when inhaled from commercially available clove cigarettes. We tested the hypothesis that eugenol directly causes lung edema through oxidant-mediated mechanisms by infusing eugenol (0.1 and 1.0 mM) into isolated
G P Meshram et al.
Mutation research, 279(4), 275-280 (1992-06-16)
Methyl isocyanate (MIC) in aqueous solution forms methylamine (MA) and N,N'-dimethylurea (DMU). MA in buffered system further converts into its salt form, methylamine hydrochloride (MAH). Therefore, MAH and DMU were evaluated for their mutagenic activity in the in vitro Ames

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