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Merck

256226

Sigma-Aldrich

N,N-Dimethyloctylamin

95%

Synonym(e):

1-Dimethylamino-octan, N-Octyldimethylamin, DMOA

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About This Item

Lineare Formel:
CH3(CH2)7N(CH3)2
CAS-Nummer:
Molekulargewicht:
157.30
Beilstein:
1698081
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22

Dampfdichte

5.4 (vs air)

Qualitätsniveau

Dampfdruck

0.8 mmHg ( 25 °C)

Assay

95%

Form

liquid

Brechungsindex

n20/D 1.424 (lit.)

bp

195 °C (lit.)

mp (Schmelzpunkt)

−57 °C (lit.)

Dichte

0.765 g/mL at 25 °C (lit.)

Funktionelle Gruppe

amine

SMILES String

CCCCCCCCN(C)C

InChI

1S/C10H23N/c1-4-5-6-7-8-9-10-11(2)3/h4-10H2,1-3H3

InChIKey

UQKAOOAFEFCDGT-UHFFFAOYSA-N

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Anwendung

N,N-Dimethyloctylamine has been employed:
  • as ion-pairing agent in quantitative estimation of thiazinamium methylsulphate in a pharmaceutical preparation by HPLC
  • as counterion in mobile phase for separation of tetracycline, tetracycline analogs and their potential impurities by reversed-phase ion-pair chromatography
  • as mobile phase in direct resolution and quantitation of (R)- and (S)-disopyramide in human plasma
  • in study of chiral separations by complexation with proteins in capillary zone electrophoresis

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

156.2 °F - closed cup

Flammpunkt (°C)

69 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Journal of Chromatography A, 635, 119-119 (1993)
J Hermansson et al.
Journal of pharmaceutical sciences, 71(2), 222-229 (1982-02-01)
Methods are presented for the separation of tetracycline, tetracycline analogs, and their potential impurities by reversed-phase ion-pair chromatography. The mobile phase consisted of a phosphate buffer with tripropylamine or N,N-dimethyloctylamine as counterions and acetonitrile as the organic modifier. The chromatographic
E Smet et al.
Journal of pharmaceutical and biomedical analysis, 23(1), 175-183 (2000-07-18)
The phenothiazine derivative thiazinamium methylsulphate is a drug with antihistaminic and anticholinergic properties, often used in some types of obstructive lung diseases. Because there is a lack of chromatographic data available for its determination, the objective of the present investigation
J Hermansson et al.
Journal of chromatography, 336(2), 321-328 (1984-12-12)
The direct resolution and quantitation of (R)- and (S)-disopyramide, isolated from human plasma, was accomplished using a chiral alpha 1-acid glycoprotein column. A LiChrosorb RP-2 column (50 X 3.0 mm I.D.) was used as a precolumn. Phosphate buffer, pH 6.20
T T Nikiforov et al.
Analytical biochemistry, 227(1), 201-209 (1995-05-01)
A reliable, simple, and cost-effective method for the immobilization of relatively short (12-30 mer) oligonucleotide probes to 96-well polystyrene plates was required in our laboratory for use in DNA hybridization-based assays. We compared three different approaches to achieve this immobilization.

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