136123

trans-Chalkon

97%

• Synonym(e): Benzylidenacetophenon
• Lineare Formel: C₆H₅CH=CHCOC₆H₅
• CAS-Nummer: 614-47-1
• Molekulargewicht: 208.26
• EG-Nummer: 210-383-8
• MDL-Nummer: MFCD00003082
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24848257
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Form: solid
• bp: 208 °C/25 mmHg (lit.)
• mp (Schmelzpunkt): 55-57 °C (lit.)
• Funktionelle Gruppe: ketone; phenyl
• SMILES String: [H]\C(=C(\[H])C(=O)c1ccccc1)c2ccccc2
• InChI: 1S/C15H12O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-12H/b12-11+
• InChIKey: DQFBYFPFKXHELB-VAWYXSNFSA-N
• Angaben zum Gen: human ... IL1B(3553) ; rat ... Ar(24208)

Beschreibung

Allgemeine Beschreibung

Open chain flavonoid that may prevent lung and forestomach cancer.

Anwendung

trans-Chalcone was used in the synthesis of cis and trans diphenyl cyclopropane. It was also used in screening of surface adsorbed species of isobutybenzene and 4-isobutylacetophenone on bulk fosfotungstic Wells-Dawson acid (H₆P₂W₁₈O₆₂.xH₂O).

Biochem./physiol. Wirkung

trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H319,H335
• P-Sätze: P261 - P264 - P270 - P271 - P301 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves