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Sodium iodoacetate

Name: Sodium iodoacetate
Brand: SIGMA

powder, ≥98%

Synonym(s):

Iodoacetic acid sodium salt

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About This Item

Linear Formula:

ICH₂COONa

CAS Number:

305-53-3

Molecular Weight:

207.93

NACRES:

NA.77

PubChem Substance ID:

24895977

UNSPSC Code:

12352202

EC Number:

206-165-7

MDL number:

MFCD00002686

Beilstein/REAXYS Number:

4009322

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Properties

Product Name

Sodium iodoacetate, ≥98%

biological source

synthetic (organic)

Quality Segment

200

assay

≥98%

form

powder

mp

208 °C (dec.) (lit.)

solubility

H₂O: 100 mg/mL

storage temp.

−20°C

SMILES string

[Na+].[O-]C(=O)CI

InChI

1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1

InChI key

AGDSCTQQXMDDCV-UHFFFAOYSA-M

Description

Application

Reagent for the modification of cysteine residues in proteins.

Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.

Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

Biochem/physiol Actions

Used to induce osteoarthritis-like lesions and functional impairment in rats, for testing of chondroprotective agents and diagnostic imaging techniques.[1]

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This Item	I9148	57858	I4386
Sigma-Aldrich I2512 Sodium iodoacetate	Sigma-Aldrich I9148 Sodium iodoacetate	Sigma-Aldrich 57858 Sodium iodoacetate	Sigma-Aldrich I4386 Iodoacetic acid
biological source synthetic (organic)	biological source synthetic (organic)	biological source -	biological source synthetic
assay ≥98%	assay ≥98%	assay ≥99.5% (NT)	assay ≥98.0% (T)
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 200
form powder	form powder	form -	form powder or flakes
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
solubility H₂O: 100 mg/mL	solubility H₂O: 0.5 M, clear, colorless	solubility methanol: 0.1 M at 20 °C, clear, colorless	solubility H₂O: soluble, clear to hazy

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pictograms

GHS06,GHS05

signalword

Danger

hcodes

H301,H314

pcodes

P260 - P270 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

406.4 °F

flash_point_c

208 °C

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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