The solubility of this product in phosphate buffered saline has not been experimentally confirmed. However, this compound is also soluble in water at 100 mg/mL. Similar rates are expected for PBS.
57858
Sodium iodoacetate
BioUltra, ≥99.5% (NT)
Synonym(s):
Iodoacetic acid sodium salt
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About This Item
Linear Formula:
ICH2COONa
CAS Number:
Molecular Weight:
207.93
UNSPSC Code:
12352106
NACRES:
NA.26
PubChem Substance ID:
EC Number:
206-165-7
Beilstein/REAXYS Number:
4009322
MDL number:
Pricing and availability is not currently available.
product line
BioUltra
Quality Segment
assay
≥99.5% (NT)
impurities
insoluble matter, passes filter test, ≤0.5% water
mp
208 °C (dec.) (lit.)
solubility
methanol: 0.1 M at 20 °C, clear, colorless
anion traces
chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤100 mg/kg
cation traces
Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤500 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg
absorption
cut-off at 335 nm in methanol at 0.1 M
storage temp.
−20°C
SMILES string
[Na+].[O-]C(=O)CI
InChI
1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1
InChI key
AGDSCTQQXMDDCV-UHFFFAOYSA-M
Application
Reagent for the modification of cysteine residues in proteins.
Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.
Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.
Other Notes
Sulfhydryl reagent[1]
1 of 1
This Item | |||
|---|---|---|---|
| assay ≥99.5% (NT) | assay ≥98% | assay ≥98% | assay ≥99.0% (NT) |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| solubility methanol: 0.1 M at 20 °C, clear, colorless | solubility H2O: 0.5 M, clear, colorless | solubility H2O: 100 mg/mL | solubility H2O: 3 M at 20 °C, clear, colorless |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. - |
| cation traces Al: ≤5 mg/kg, Ba: ≤5 mg/kg, Ca: ≤10 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤500 mg/kg, Mg: ≤5 mg/kg, Mo: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg, As: ≤0.1 mg/kg, Cd: ≤5 mg/kg, Fe: ≤5 mg/kg, Mn: ≤5 mg/kg, Sr: ≤5 mg/kg, Bi: ≤5 mg/kg, Li: ≤5 mg/kg, Cr: ≤5 mg/kg, Ni: ≤5 mg/kg | cation traces Al: ≤0.0005%, Ca: ≤0.001%, Cu: ≤0.001%, Fe: ≤0.0005%, K: ≤0.02%, Mg: ≤0.0005%, NH4+: ≤0.05%, Pb: ≤0.001%, Zn: ≤0.0005% | cation traces - | cation traces Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤10 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤10 mg/kg, Zn: ≤5 mg/kg |
| mp 208 °C (dec.) (lit.) | mp 208 °C (dec.) (lit.) | mp 208 °C (dec.) (lit.) | mp >300 °C (dec.) (lit.) |
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
406.4 °F
flash_point_c
208 °C
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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The solubility of product #57858 is only described in methanol. Is this product also soluble in PBS?
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