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725986

Sigma-Aldrich

Trimethylsilanol

≥97.5% (GC)

Synonym(s):

TMS, TMSiOH, Hydroxytrimethylsilane

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About This Item

Linear Formula:
(CH3)3SiOH
CAS Number:
1066-40-6
Molecular Weight:
90.20
Beilstein:
1361356
EC Number:
213-914-1
MDL number:
MFCD02751657
UNSPSC Code:
12352103
PubChem Substance ID:
329764205
NACRES:
NA.22

Assay

≥97.5% (GC)

form

liquid

SMILES string

C[Si](C)(C)O

InChI

1S/C3H10OSi/c1-5(2,3)4/h4H,1-3H3

InChI key

AAPLIUHOKVUFCC-UHFFFAOYSA-N

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Application

Trimethylsilanol (TMS) can be used to prepare tris(trimethylsiloxy) aluminum (I) by reacting with triethylaluminum.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H332,H412

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

44.6 °F - closed cup

Flash Point(C)

7 °C - closed cup

Certificates of Analysis (COA)

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Saegusa T, et al.
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Establish an effective experimental strategy to determine the compatibility of rubber closures for drugs. Various types of rubber closures with different compositions are available for drug packaging. Many additives of rubber closures can be released from rubber closures and may
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A convenient and efficient method for the cleavage of 1,3-oxazolidin-5-ones and 1,3-oxazolidin-2-ones utilising potassium trimethylsilanolate in tetrahydrofuran is described. The benzyloxycarbonyl-protecting group is readily removed under the reaction conditions, whereas the N-benzoyl group is stable. A synthesis of (R)-salmeterol exploiting
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