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T1660

Sigma-Aldrich

Nε,Nε,Nε-Trimethyllysine hydrochloride

≥97% (TLC)

Synonym(s):

1-Pentanaminium, 5-amino-5-carboxy-N,N,N-trimethyl-, chloride (1:1), (5S)-

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About This Item

Empirical Formula (Hill Notation):
C9H20N2O2 · HCl
CAS Number:
55528-53-5
Molecular Weight:
224.73
MDL number:
MFCD06795777
UNSPSC Code:
12352202
PubChem Substance ID:
24899984
NACRES:
NA.26

Quality Level

200

Assay

≥97% (TLC)

form

powder

contains

salts and water as balance

composition

Amino acid content, ~75%

technique(s)

LC/MS: suitable

color

white

storage temp.

−20°C

SMILES string

[Cl-].C[N+](C)(C)CCCC[C@H](N)C(O)=O

InChI

1S/C9H20N2O2.ClH/c1-11(2,3)7-5-4-6-8(10)9(12)13;/h8H,4-7,10H2,1-3H3;1H/t8-;/m0./s1

InChI key

ZKIJKCHCMFGMCM-QRPNPIFTSA-N

Related Categories

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Naomi van Vlies et al.
The FEBS journal, 274(22), 5845-5851 (2007-10-20)
The first enzyme of carnitine biosynthesis is the mitochondrial 6-N-trimethyllysine dioxygenase, which converts 6-N-trimethyllysine to 3-hydroxy-6-N-trimethyllysine. Using progressive membrane solubilization with digitonin and protease protection experiments, we show that this enzyme is localized in the mitochondrial matrix. Latency experiments with
Yongkun Wei et al.
Molecular carcinogenesis, 47(9), 701-706 (2008-01-08)
Methylation of lysine 27 on histone H3 (H3K27) by the EZH2 complex is an epigenetic mark that mediates gene silencing. EZH2 is overexpressed in many cancers and correlates with poor prognosis in both breast and prostate cancers. However, the status
Maren Fischer et al.
The British journal of nutrition, 101(2), 190-196 (2008-05-22)
This study was performed to investigate whether dietary lysine concentration influences the carnitine status of pigs. Therefore, an experiment with twenty young pigs with an average body weight of 21 kg was performed which were fed either a control diet
Zhenyu Lu et al.
Journal of the American Chemical Society, 131(41), 14928-14931 (2009-10-01)
Histone modifications are implicated in epigenetic inheritance and are of central importance in regulating chromatin structure and gene expression. A prototype example is the trimethylation (Me3) of lysine 9 on histone 3 (H3), which is a readout by an aromatic
Lynnette M A Dirk et al.
Biochemistry, 46(12), 3905-3915 (2007-03-07)
Processive versus distributive methyl group transfer was assessed for pea Rubisco large subunit methyltransferase, a SET domain protein lysine methyltransferase catalyzing the formation of trimethyllysine-14 in the large subunit of Rubisco. Catalytically competent complexes between an immobilized form of des(methyl)
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