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Key Documents

F3381

Sigma-Aldrich

Fast Red Violet LB Salt

Dye content ≥90%, Powder

Synonym(s):

5-Chloro-4-benzamido-2-methylbenzenediazonium chloride hemi(zinc chloride) salt

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About This Item

Linear Formula:
C14H11Cl2N3O · ½ZnCl2
CAS Number:
Molecular Weight:
376.31
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

Fast Red Violet LB Salt, Dye content ≥90 %

form

powder

Quality Level

composition

Dye content, ≥90%

solubility

H2O: 1 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Cl-].Cc1cc(NC(=O)c2ccccc2)c(Cl)cc1[N+]#N

InChI

1S/C14H10ClN3O.ClH/c1-9-7-13(11(15)8-12(9)18-16)17-14(19)10-5-3-2-4-6-10;/h2-8H,1H3;1H

InChI key

SARKXLKWFKNUMR-UHFFFAOYSA-N

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General description

Fast Red Violet LB Salt, also known as 4′-amino-2′-chloro-5′-methylbenzanilide. It is a lipophilic amine with an aromatic system of moderate size and a hydrophilic diazonium cation. The diazonium salt is available commercially as a zinc chloride double salt. It comprises ≥90% dye content.

Application

  • Fast Red Violet LB Salt is suitable for quantitating alkaline phosphatase through histochemical, hematological, histological, and flow cytometric methods.
  • It has been used to study the role of TNF-α during fracture healing.
  • has been used for the detection of tartrate-resistant acid phosphatase (TRAP) in tissue sections.

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Three-dimensional reconstruction of fracture callus morphogenesis.
Gerstenfeld LC
The Journal of Histochemistry and Cytochemistry, 54, 1215-1215 (2006)
Impaired fracture healing in the absence of TNF-alpha signaling: the role of TNF-alpha in endochondral cartilage resorption
Gerstenfeld, et al.
Journal of Bone and Mineral Research, 18(9), 1584?1592-1584?1592 (2003)
Tatsuya Yoshida et al.
Journal of orthopaedic surgery and research, 4, 31-31 (2009-08-05)
Pasteurized bone grafting is used following the excision of a bone tumor for the purpose of eliminating neoplastic cells while preserving bone-inducing ability. In the hopes of guaranteeing the most favourable results, the establishment of an animal model has been
Comparison of effects of the bisphosphonate alendronate versus the RANKL inhibitor denosumab on murine fracture healing.
Gerstenfeld LC
Journal of Bone and Mineral Research, 24, 196-196 (2009)
L C Gerstenfeld et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 18(9), 1584-1592 (2003-09-13)
TNF-alpha is a major inflammatory factor that is induced in response to injury, and it contributes to the normal regulatory processes of bone resorption. The role of TNF-alpha during fracture healing was examined in wild-type and TNF-alpha receptor (p55(-/-)/p75(-/-))-deficient mice.

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