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Key Documents

P46105

Sigma-Aldrich

Piperidine hydrochloride

99%

Synonym(s):

Piperidinium chloride

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About This Item

Empirical Formula (Hill Notation):
C5H11N · HCl
CAS Number:
Molecular Weight:
121.61
Beilstein:
3611699
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

vapor density

2.94 (vs air)

Quality Level

vapor pressure

63.6 mmHg ( 37.8 °C)

Assay

99%

form

powder

mp

245-248 °C (lit.)

SMILES string

Cl[H].C1CCNCC1

InChI

1S/C5H11N.ClH/c1-2-4-6-5-3-1;/h6H,1-5H2;1H

InChI key

VEIWYFRREFUNRC-UHFFFAOYSA-N

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Application

Reagent for synthesis of:
  • Quinoline selenium compounds
  • Peripheral seratonin 5-HT3 receptor ligands

Reactant for synthesis of phthalazinone derivatives as topically active phosphodiesterase 4 inhibitors

Reactant for:
  • Mannich reactions
  • Asymmetric hydrogenation of quinolines
  • Chemoselective reductive amination of carbonyl compounds

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Qingtong Wang et al.
Scientific reports, 7, 45364-45364 (2017-03-30)
T cell infiltration to synovial tissue is an early pathogenic mechanism of rheumatoid arthritis (RA). In the present work, we reveal that G protein coupled receptor kinase 2 (GRK2) is abundantly expressed in T cells of collagen-induced arthritis (CIA). A
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FEBS open bio, 11(1), 10-25 (2020-11-29)
Deoxyhypusine synthase transfers an aminobutyl moiety from spermidine to the eukaryotic translation initiation factor 5A (eIF5A) in the first step of eIF5A activation. This exclusive post-translational modification is conserved in all eukaryotes. Activated eIF5A has been shown to be essential
Željko Pavković et al.
Progress in neuro-psychopharmacology & biological psychiatry, 96, 109733-109733 (2019-08-17)
Adolescent neurodevelopment confer vulnerability to the actions of treatments that produce adaptations in neurocircuitry underlying motivation, impulsivity and reward. Considering wide usage of a sedative-hypnotic agent propofol in clinical practice, we examined whether propofol is a challenging treatment for peripubertal
Reza Shamsimeymandi et al.
Archiv der Pharmazie, 352(7), e1800352-e1800352 (2019-05-29)
A series of novel chroman-4-one derivatives were designed and synthesized successfully with good to excellent yield (3a-l). In addition, the obtained products were evaluated for their cholinesterase (ChE) inhibitory activities. The results show that among the various synthesized compounds, analogs
Xiao-Xi Huang et al.
Nucleic acids research, 42(13), 8719-8731 (2014-06-19)
Ligands that can interact specifically with telomeric multimeric G-quadruplexes could be developed as promising anticancer drugs with few side effects related to other G-quadruplex-forming regions. In this paper, a new cationic porphyrin derivative, m-TMPipEOPP, was synthesized and characterized. Its multimeric

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