A55500
2-Aminofluorene
98%
Synonym(s):
2-Fluorenamine, 2-Fluorenylamine
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About This Item
Empirical Formula (Hill Notation):
C13H11N
CAS Number:
Molecular Weight:
181.23
Beilstein:
1945861
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
98%
form
powder
mp
124-128 °C (lit.)
SMILES string
Nc1ccc-2c(Cc3ccccc-23)c1
InChI
1S/C13H11N/c14-11-5-6-13-10(8-11)7-9-3-1-2-4-12(9)13/h1-6,8H,7,14H2
InChI key
CFRFHWQYWJMEJN-UHFFFAOYSA-N
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Related Categories
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 2 - Carc. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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The aromatic amine carcinogen 2-aminofluorene (AF) forms covalent adducts with DNA, predominantly with guanine at the C8 position. Such lesions are bypassed by Y-family polymerases such as Dpo4 via error-free and error-prone mechanisms. We show that Dpo4 catalyzes elongation from
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