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930180

Sigma-Aldrich

Linear polyglycerol solution

average Mn 10,000, in H2O

Synonym(s):

Polyglycerol, Polyglycidol

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About This Item

Linear Formula:
C7H7O(C3H6O2)mH
MDL number:
MFCD00016633
UNSPSC Code:
12352112
NACRES:
NA.25

form

viscous liquid (or Paste)

Quality Level

100

mol wt

average Mn 10,000

composition

Water Content, ≤50 wt. %

concentration

in H2O

color

colorless to yellow, and White to Yellow

density

1.164 g/mL

SMILES string

[H]OC(CO)COCC1=CC=CC=C1

InChI

1S/C10H14O3/c11-6-10(12)8-13-7-9-4-2-1-3-5-9/h1-5,10-12H,6-8H2

InChI key

LWCIBYRXSHRIAP-UHFFFAOYSA-N

General description

Polyglycerol is a highly biocompatible polymer with a main chain structure similar to that of poly(ethylene glycol) (PEG). In contrast to PEG, which only bears a maximum of two functional groups, limiting possibilities for derivatization, polyglycerol carries a hydroxyl side group in every repeating unit. The hydroxyl groups in polyglycerol not only increase the hydrophilicity of this polymer, but also allows for its modification, leading to polymers with a wide range of different functional groups, as well as conjugation to biomolecules.

Application

As a promising PEG alternative, polyglycerol and polyglycerol-containing polymers have great potential in applications including-anti-fouling -drug delivery-tissue engineering-diagnostics and biosensors.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

>230.9 °F

Flash Point(C)

> 110.5 °C

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Anja Thomas et al.
Biomacromolecules, 15(6), 1935-1954 (2014-05-13)
Polyglycerols (sometimes also called "polyglycidols") represent a class of highly biocompatible and multihydroxy-functional polymers that may be considered as a multifunctional analogue of poly(ethylene glycol) (PEG). Various architectures based on a polyglycerol scaffold are feasible depending on the monomer employed.

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