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901154

Sigma-Aldrich

2-(2-(2-Ethoxyethoxy)ethoxy)ethanamine

Synonym(s):

3,6,9-Trioxaundecylamine, N-[2-(2-(2-Ethoxyethoxy)ethoxy)ethyl]amine

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About This Item

Empirical Formula (Hill Notation):
C8H19NO3
CAS Number:
Molecular Weight:
177.24
MDL number:
UNSPSC Code:
12352116
NACRES:
NA.22

form

liquid

Quality Level

density

0.974

InChI

1S/C8H19NO3/c1-2-10-5-6-12-8-7-11-4-3-9/h2-9H2,1H3

InChI key

WWJVRDMJNJTOBL-UHFFFAOYSA-N

Application

2-(2-(2-Ethoxyethoxy)ethoxy)ethanamine can be used as a reactant to synthesize:
  • 2-(2-(2-(2-Ethoxyethoxy)ethoxy)ethyl)-4-nitroisoindoline-1,3-dione, a key intermediate used to prepare excited-state intramolecular proton transfer (ESIPT)-based fluorescent probe for the detection of palladium.
  • Acetamidine derivatives by condensation reaction with N,N-dimethylacetamide dimethyl acetal.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

230.0 °F

Flash Point(C)

110 °C


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A water soluble ESIPT-based fluorescent chemodosimeter for the ratiometric detection of palladium ions in aqueous solution and its application in live-cell imaging
Huang J, et al.
New. J. Chem., 42(19), 15587-15592 (2018)
Jitendra R Harjani et al.
The Journal of organic chemistry, 76(6), 1683-1691 (2011-02-15)
The condensation of primary amine with N,N-dimethylacetamide dimethyl acetal yields a mixture of acetamidine and imidate ester. The product distribution in this reaction depends on the temperature, solvent, and structure of the primary amine. It is possible to suppress the

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