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695106

Sigma-Aldrich

p-Phenylenediamine

sublimed, ≥99%

Synonym(s):

1,4-Benzenediamine, 1,4-Diaminobenzene, 1,4-Phenylenediamine

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About This Item

Linear Formula:
C6H4(NH2)2
CAS Number:
106-50-3
Molecular Weight:
108.14
Beilstein:
742029
EC Number:
203-404-7
MDL number:
MFCD00007901
UNSPSC Code:
12352100
PubChem Substance ID:
329761716
NACRES:
NA.22

vapor density

3.7 (vs air)

Quality Level

200

vapor pressure

1.08 mmHg ( 100 °C)

description

anti-fade reagent

Assay

≥99%

form

sublimed

bp

267 °C (lit.)

mp

138-143 °C (lit.)

SMILES string

Nc1ccc(N)cc1

InChI

1S/C6H8N2/c7-5-1-2-6(8)4-3-5/h1-4H,7-8H2

InChI key

CBCKQZAAMUWICA-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 1 Oral

Target Organs

Kidney,Heart,Musculo-skeletal system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000238745
0000288136
MKBZ1484V
MKBV9954V
MKBN5055V

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Jacob Pontoppidan Thyssen et al.
Contact dermatitis, 59(6), 327-343 (2008-12-17)
Many women and men now dye their hair. p-Phenylenediamine (PPD) is a frequent and important component of permanent hair dye products; exposure to it may cause allergic contact sensitization, acute dermatitis, and severe facial oedema. To increase our understanding of
Daniel P Poole et al.
American journal of physiology. Gastrointestinal and liver physiology, 309(4), G248-G259 (2015-07-04)
Activated G protein-coupled receptors traffic to endosomes and are sorted to recycling or degradative pathways. Endosomes are also a site of receptor signaling of sustained and pathophysiologically important processes, including inflammation. However, the mechanisms of endosomal sorting of receptors and
Ryosuke Nagashima et al.
The Journal of cell biology, 218(5), 1511-1530 (2019-03-03)
Although chromatin organization and dynamics play a critical role in gene transcription, how they interplay remains unclear. To approach this issue, we investigated genome-wide chromatin behavior under various transcriptional conditions in living human cells using single-nucleosome imaging. While transcription by
Laura M Pot et al.
Contact dermatitis, 68(4), 193-207 (2013-03-21)
Although p-phenylenediamine (PPD) has been recognized as an extreme sensitizer for many years, the exact mechanism of sensitization has not been elucidated yet. Penetration and the ability to bind to proteins are the first two hurdles that an allergen has
Satoru Ide et al.
Science advances, 6(42) (2020-10-16)
The nucleolus is a nuclear body with multiphase liquid droplets for ribosomal RNA (rRNA) transcription. How rRNA transcription is regulated in the droplets remains unclear. Here, using single-molecule tracking of RNA polymerase I (Pol I) and chromatin-bound upstream binding factor
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