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512346

Sigma-Aldrich

5-Formyl-2-furanylboronic acid

≥95%

Synonym(s):

5-Formyl-2-furanboronic acid

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About This Item

Empirical Formula (Hill Notation):
C5H5BO4
CAS Number:
Molecular Weight:
139.90
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥95%

form

solid

mp

136 °C (dec.) (lit.)

functional group

aldehyde

SMILES string

OB(O)c1ccc(C=O)o1

InChI

1S/C5H5BO4/c7-3-4-1-2-5(10-4)6(8)9/h1-3,8-9H

InChI key

JUWYQISLQJRRNT-UHFFFAOYSA-N

Application

Reactant involved in Suzuki coupling for synthesis of stable dye-senstitized solar cells

Reactant involved in synthesis of biologically active molecules including:
  • Heteroarylation for the synthesis of HIF-1 inhibitors
  • Disalicylic acid-furanyl derivatives to inhibit ephrin binding
  • HIV-1 integrase inhibitors
  • Epidermal growth factor receptor inhibitors

Other Notes

Contains varying amounts of anhydride

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Qi Xia et al.
ACS applied materials & interfaces, 10(20), 17081-17088 (2018-05-03)
Effective long-term monitoring of tumor growth is significant for the evaluation of cancer therapy. Aggregation-induced emission-active near-infrared (NIR) fluorescent organic nanoparticles (TPFE-Rho dots) are designed and synthesized for long-term in vitro cell tracking and in vivo monitoring of tumor growth.
Marika Tiberi et al.
Antimicrobial agents and chemotherapy, 58(6), 3043-3052 (2014-03-13)
We report here the synthesis of 2-aminothiazolones along with their biological properties as novel anti-HIV agents. Such compounds have proven to act through the inhibition of the gp120-CD4 protein-protein interaction that occurs at the very early stage of the HIV-1

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