108413

Methyl chloroacetate

99%

• Synonym(s): Chloroacetic acid methyl ester, Methyl 2-chloroacetate
• Linear Formula: ClCH₂COOCH₃
• CAS Number: 96-34-4
• Molecular Weight: 108.52
• Beilstein: 506255
• EC Number: 202-501-1
• MDL number: MFCD00000931
• UNSPSC Code: 12352100
• PubChem Substance ID: 24846666
• NACRES: NA.22

Properties

• vapor density: 3.8 (vs air)
• Quality Level: 100
• vapor pressure: 10 mmHg ( 25 °C); 5.25 mmHg ( 20 °C)
• Assay: 99%
• autoignition temp.: 869 °F
• expl. lim.: 18.5 %
• refractive index: n20/D 1.422 (lit.)
• bp: 130 °C/740 mmHg (lit.)
• mp: −33 °C (lit.)
• solubility: H₂O: insoluble; alcohol: miscible; diethyl ether: miscible
• density: 1.238 g/mL at 25 °C (lit.)
• functional group: chloro; ester
• SMILES string: COC(=O)CCl
• InChI: 1S/C3H5ClO2/c1-6-3(5)2-4/h2H2,1H3
• InChI key: QABLOFMHHSOFRJ-UHFFFAOYSA-N

Description

General description

Methyl chloroacetate acts as extraction solvent during the separation of neutral compounds with concentration enhancement using coupling liquid–liquid semimicroextraction with micellar electrokinetic chromatography through on-capillary decomposition. It regenerates the PdCl₂-CuCl₂/activated carbon catalyst used for synthesis of dimethyl carbonate.

Application

Methyl chloroacetate was used in the preparation of (carboxymethyl) trimethylammonium chloride esters. It may be used in the synthesis of octakis-(carbethoxymethoxy)calix[8]arene.

Safety Information

• Pictograms: GHS02,GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H226,H301 + H331,H315,H318,H335
• Precautionary Statements: P210 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 116.6 °F - closed cup
• Flash Point(C): 47 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves