107271

(±)-3-Chloro-1,2-propanediol

98%

• Synonym(s): α-Chlorohydrin, α-Glycerol chlorohydrin, α-Monochlorohydrin, 3-MCPD
• Linear Formula: ClCH₂CH(OH)CH₂OH
• CAS Number: 96-24-2
• Molecular Weight: 110.54
• Beilstein: 635684
• EC Number: 202-492-4
• MDL number: MFCD00004712
• UNSPSC Code: 12352100
• PubChem Substance ID: 24846761
• NACRES: NA.22

Properties

• vapor pressure: 0.04 mmHg ( 25 °C)
• Assay: 98%
• refractive index: n20/D 1.480 (lit.)
• bp: 213 °C (lit.)
• solubility: H₂O: soluble; alcohol: soluble; diethyl ether: soluble
• density: 1.322 g/mL at 25 °C (lit.)
• functional group: chloro
• SMILES string: OCC(O)CCl
• InChI: 1S/C3H7ClO2/c4-1-3(6)2-5/h3,5-6H,1-2H2
• InChI key: SSZWWUDQMAHNAQ-UHFFFAOYSA-N

Description

General description

3-Chloro-1,2-propanediol undergoes enantioselective transformation to (R)-3-chloro-1,2-propanediol by the cell extract of Corynebacterium sp. strain N-1074 . It is a contaminant found in food in free (diol) form as well as in an esterified (with fatty acids) form.

Application

(±)-3-Chloro-1,2-propanediol may be used in manufacture of dye intermediates.

Biochem/physiol Actions

3-Chloro-1,2-propanediol is a potent rodent chemosterilant.

Safety Information

• Pictograms: GHS06,GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H290,H301,H315,H318,H330,H351,H360FD,H370,H372
• Precautionary Statements: P202 - P234 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Carc. 2 - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Irrit. 2 - STOT RE 1 - STOT SE 1
• Target Organs: Kidney, Testes
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves