1313006

Hydralazine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 1-Hydrazinophthalazine hydrochloride
• Empirical Formula (Hill Notation): C₈H₈N₄ · HCl
• CAS Number: 304-20-1
• Molecular Weight: 196.64
• NACRES: NA.24
• PubChem Substance ID: 329750018
• UNSPSC Code: 41116107
• MDL number: MFCD00135998

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: hydralazine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule); pharmaceutical
• format: neat
• SMILES string: Cl[H].N\N=C1/N=NC=C2C=CC=CC12
• InChI: 1S/C8H8N4.ClH/c9-11-8-7-4-2-1-3-6(7)5-10-12-8;/h1-5,7H,9H2;1H/b11-8-;
• InChI key: SECXUXOCDLQOBI-MKFZHGHUSA-N

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hydralazine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Hydralazine Hydrochloride Injection
• Hydralazine Hydrochloride Tablets

Biochem/physiol Actions

Inhibits DNA methyltransferase and modulates epigenetic regulation of gene expression. Non-selective MAO-A/B inhibitor; antihypertensive; semicarbazide-sensitive amine oxidase inhibitor.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Codes: H301,H315,H319,H335
• Precautionary Statements: P301 + P330 + P331 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable