T4571

Taurine

• Synonym(s): 2-Aminoethanesulfonic acid
• Linear Formula: NH₂CH₂CH₂SO₃H
• CAS Number: 107-35-7
• Molecular Weight: 125.15
• EC Number: 203-483-8
• UNSPSC Code: 12352106
• NACRES: NA.26
• Beilstein/REAXYS Number: 1751215
• MDL number: MFCD00008197

Properties

• biological source: non-animal source
• Quality Segment: 400
• assay: ≥98.5%
• form: crystalline powder
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, heavy metals, trace metals, tested
• mp: >300 °C (lit.)
• solubility: H₂O: ≥100 mg/mL
• application(s): downstream processes; pharma/biopharma processes
• foreign activity: cytotoxicity, tested
• SMILES string: NCCS(O)(=O)=O
• InChI: 1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
• InChI key: XOAAWQZATWQOTB-UHFFFAOYSA-N
• Gene Information: rat ... Ppm1a(24666)

Description

General description

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.

Application

Taurine is a derivative of the sulfur-containing (sulfhydryl) amino acid cysteine. Taurine is one of the few known naturally occurring sulfonic acids. It is a conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism. It can be used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Biochem/physiol Actions

Non-selective endogenous agonist at glycine receptors.

Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Gloves