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SML3775

Desthiobiotin-Phenol

≥98% (HPLC), peroxidase sensitive probe, powder

Synonym(s):

(4R,5S)-N-[2-(4-Hydroxyphenyl)ethyl]-5-methyl-2-oxo-4-imidazolidinehexanamide, DBP, Desthiobiotin-Tyramide, N-(4-Hydroxyphenethyl)-6-((4R,5S)-5-methyl-2-oxoimidazolidin-4-yl)hexanamide, d-Desthiobiotin-Phenol

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About This Item

Empirical Formula (Hill Notation):
C18H27N3O3
CAS Number:
Molecular Weight:
333.43
UNSPSC Code:
12352200
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
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Product Name

Desthiobiotin-Phenol, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

A peroxidase-sensitive desthiobiotin-phenol (DBP) probe that offers more efficient recovery of DBP-labeled peptides from streptavidin beads and stronger mass spectrometry intensity of modified membrane proteins and achieves greater sensitivity for tyrosine residues detection. DBP shows a similar reactivity to the protein when it is converted to the phenoxyl radical state as biotin-phenol/biotin-tyramide (BP) in ascorbate peroxidase (APEX) proximity labeling. DBP exhibits reduced affinity to streptavidin and does not suffer from sulfur oxidation issue during the radical generation.
APEX (ascorbate peroxidase) proximity tyrosine site label, a sulfur-free Biotin-Tyramide analog that can be displaced competitively by biotin

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description

≥98% (HPLC)

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description

≥95% (HPLC), powder, amine-reactive NHS tag

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

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assay

≥95% (HPLC)

form

powder

form

powder

form

paste

form

powder

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

storage temp.

-10 to -25°C

storage temp.

-10 to -25°C

storage temp.

−20°C

storage temp.

-10 to -25°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

-

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

white to beige

color

-

color

white to beige


WGK

WGK 3

Storage Class

11 - Combustible Solids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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