There is no direct information available for this product regarding sonication in DMSO. However, for similar small molecule products, sonication is commonly recommended to aid dissolution in DMSO, especially if warming and vortexing are insufficient.
SML3689
S-Geranylgeranyl-L-glutathione
≥98% (HPLC)
Synonym(s):
(S)-2-Amino-5-((R)-1-(carboxymethylamino)-1-oxo-3-((2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenylthio)propan-2-ylamino)-5-oxopentanoic acid, GGG
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About This Item
Empirical Formula (Hill Notation):
C30H49N3O6S
CAS Number:
Molecular Weight:
579.79
UNSPSC Code:
12352200
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
Pricing and availability is not currently available.
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
2-8°C
SMILES string
OC([C@@H](N)CCC(N[C@H](C(NCC(O)=O)=O)CSC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)=O)=O
InChI
1S/C30H49N3O6S/c1-21(2)9-6-10-22(3)11-7-12-23(4)13-8-14-24(5)17-18-40-20-26(29(37)32-19-28(35)36)33-27(34)16-15-25(31)30(38)39/h9,11,13,17,25-26H,6-8,10,12,14-16,18-20,31H2,1-5H3,(H,32,37)(H,33,34)(H,35,36)(H,38,39)/b22-11+,23-13+,24-17+/t25-,26-/m0/s1
InChI key
BAJIBEVLRWVBAZ-DPRMOSMCSA-N
Biochem/physiol Actions
Potent and selective ligand for P2RY8
The metabolite S-Geranylgeranyl-L-glutathione (GGG) is a potent and selective ligand for P2RY8, a Gα13-coupled receptor. GGG promotes internalization of P2RY8 and inhibits the migration of P2RY8-expressing cells (10 – 100 nM range in WEHI-231 cells). Extracellular GGG is shown to be actively transported by ABCC1 (ATP-binding cassette subfamily C member 1) and catabolized by GGT5 (gamma-glutamyltransferase-5) to S-geranylgeranyl-L-Cys-Gly plus glutathione.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description Avanti Research™ - A Croda Brand | description - | description Avanti Research™ - A Croda Brand |
| form powder | form powder | form oil | form methyl acetate solution |
| assay ≥98% (HPLC) | assay >99% (TLC) | assay ≥98% (HPLC) | assay >99% (TLC) |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level - |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| solubility DMSO: 2 mg/mL, clear (Warmed) | solubility - | solubility DMSO: >5 mg/mL | solubility - |
| color white to beige | color - | color clear | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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Can S-geranyl-geranyl-glutathione be sonicated when dissolving it in DMSO?
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