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About This Item
Empirical Formula (Hill Notation):
C12H12AuCl2N2O2 · PF6
CAS Number:
Molecular Weight:
629.07
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥97% (NMR)
Form:
powder
Pricing and availability is not currently available.
assay
≥97% (NMR)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
[Cl-][Au+3]1([N]2=C(C=C(C=C2)OC)C3=[N]1C=CC(OC)=C3)[Cl-].F[P-](F)(F)(F)(F)F
Biochem/physiol Actions
AubipyOMe is a potent inhibitor of tartrate resistant acid phosphatase (TRAP/ACP5), a metalloenzyme expressed in activated osteoclasts and in macrophages. AubipyOMe exhibited IC50 values of 1.3 μM for TRAP5a and 1.8 μM for TRAP5b and inhibited TRAP activity in murine macrophage and human lung tissue extracts.
Tartrate resistant acid phosphatase (TRAP/ACP5) inhibitor
1 of 1
This Item | |||
|---|---|---|---|
| description ≥97% (NMR) | description ≥95% (HPLC) | description ≥95.0% (H-NMR) | description ≥97.0% (H-NMR) |
| assay ≥97% (NMR) | assay ≥95% (HPLC) | assay ≥95.0% (H-NMR) | assay ≥97.0% (H-NMR) |
| form powder | form powder | form crystals | form crystals |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - | storage temp. - |
| solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility - | solubility - |
| color white to beige | color white to beige | color - | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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