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SML0916

CaCCinh-A01

≥98% (HPLC)

Synonym(s):

6-(1,1-Dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C18H21NO4S
CAS Number:
Molecular Weight:
347.43
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

[s]1c2c(c(c1NC(=O)c3[o]ccc3)C(=O)O)CCC(C2)C(C)(C)C

InChI

1S/C18H21NO4S/c1-18(2,3)10-6-7-11-13(9-10)24-16(14(11)17(21)22)19-15(20)12-5-4-8-23-12/h4-5,8,10H,6-7,9H2,1-3H3,(H,19,20)(H,21,22)

InChI key

ACLUEOBQFRYTQS-UHFFFAOYSA-N

Biochem/physiol Actions

CaCCinh-A01 is a potent calcium-activated chloride channel (CaCC) inhibitor that fully inhibits CaCC current in human bronchial and intestinal cells. CaCCinh-A01 does not inhibit CFTR.
CaCCinh-A01 is a potent calcium-activated chloride channel (CaCC) inhibitor.
CaCCinh-A01 is a TMEM16A (transmembrane member 16A) inhibitor. It also blocks anoctamin-1 (ANO1) and decreases cell viability and represses cell migration.

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This Item
208293SML0209SML2413
description

≥98% (HPLC)

description

The Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 controls the biological activity of Calcium-activated Chloride Channel.

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

solid

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 50 mg/mL, pale yellow

solubility

DMSO: ≥5 mg/mL at 60 °C

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

off-white

color

white to beige

color

white to light brown


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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