Key Documents

Amprenavir

Name: Amprenavir
Brand: SIGMA

≥98% (HPLC), HIV Protease Inhibitor, powder

Synonym(s):

N-[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic acid (3S)-tetrahydro-3-furanyl ester, VX-478

Select a Size

Change View

Size/SKU	Availability	Price

About This Item

Empirical Formula (Hill Notation):

C₂₅H₃₅N₃O₆S

CAS Number:

161814-49-9

Molecular Weight:

505.63

UNSPSC Code:

12352200

NACRES:

NA.77

Assay:

≥98% (HPLC)

Form:

powder

Pricing and availability is not currently available.

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Amprenavir, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D +8 to +12°, c = 0.5 in methanol

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

−20°C

SMILES string

[S](=O)(=O)(N(C[C@@H](O)[C@@H](NC(=O)O[C@@H]3COCC3)Cc2ccccc2)CC(C)C)c1ccc(cc1)N

InChI

1S/C25H35N3O6S/c1-18(2)15-28(35(31,32)22-10-8-20(26)9-11-22)16-24(29)23(14-19-6-4-3-5-7-19)27-25(30)34-21-12-13-33-17-21/h3-11,18,21,23-24,29H,12-17,26H2,1-2H3,(H,27,30)/t21-,23-,24+/m0/s1

InChI key

YMARZQAQMVYCKC-OEMFJLHTSA-N

Description

General description

Amprenavir is a second-generation drug derived from hydroxyethylamine sulfonamide.

Biochem/physiol Actions

Amprenavir is an antiretroviral HIV Protease Inhibitor.

Amprenavir is an antiretroviral HIV Protease Inhibitor. It is the active metabolite of fosamprenavir.

Protease inhibition results in inactive and immature virus.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	SML1222	SML0491	1370101
Sigma-Aldrich SML0685 Amprenavir	Sigma-Aldrich SML1222 Lopinavir	Sigma-Aldrich SML0491 Ritonavir	USP 1370101 Lopinavir
description ≥98% (HPLC)	description ≥98% (HPLC)	description ≥98% (HPLC)	description United States Pharmacopeia (USP) Reference Standard
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay -
form powder	form powder	form powder	form powder
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level -
storage temp. −20°C	storage temp. −20°C	storage temp. room temp	storage temp. 2-8°C
solubility DMSO: 20 mg/mL, clear	solubility DMSO: 20 mg/mL, clear	solubility DMSO: 10 mg/mL (clear solution, warmed)	solubility methylene chloride: freely soluble, water: practically insoluble, chloroform: soluble, isopropanol: soluble, methanol: freely soluble
color white to beige	color white to beige	color white to beige	color white to off-white

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.