SCP0002
Acetyl-Amyloid β 25-35
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About This Item
Empirical Formula (Hill Notation):
C47H83N13O15S1
Molecular Weight:
1102.31
NACRES:
NA.32
UNSPSC Code:
12352202
Pricing and availability is not currently available.
General description
Amyloid-β (Aβ) peptides are a major component of the senile plaques characteristic of the Alzheimer brain. It is a type- I transmembrane protein. The amyloid β precursor protein is cleaved to amyloid peptides 36-43 amino acids in length. Aβ (25-35) represents the region that aggregates during plaque formation and is a functional domain implicated in both neurotrophic and neurotoxic effects. The gene encoding amyloid-β is localized on human chromosome 21. Acetylation may improve stability in in vitro and in vivo assays.
Application
Acetyl-Amyloid β 25-35 has been used to prepare rat models with Alzheimer′s disease.
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This Item | |||
|---|---|---|---|
| description - | description ≥90% (HPLC), powder | description ≥90% (HPLC), lyophilized powder | description ≥90% (HPLC) |
| assay ≥95% (HPLC) | assay ≥90% (HPLC) | assay ≥90% (HPLC) | assay ≥90% (HPLC) |
| form lyophilized | form powder | form lyophilized powder | form powder |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| Gene Information human ... APP(351) | Gene Information human ... APP(351) | Gene Information human ... APP(351) | Gene Information human ... APP(351) |
| storage condition protect from light | storage condition - | storage condition - | storage condition - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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