SAB1303130

ANTI-HSD17B2 (CENTER) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Synonym(s): 17-beta-HSD 2, 17-beta-hydroxysteroid dehydrogenase type 2, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, E2DH, EDH17B2, Estradiol 17-beta-dehydrogenase 2, HSD17B2, Microsomal 17-beta-hydroxysteroid dehydrogenase, Testosterone 17-beta-dehydrogenase
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 42785 Da
• species reactivity: human
• technique(s): flow cytometry: 1:10-1:50; immunohistochemistry: 1:10-1:50; western blot: 1:1000
• UniProt accession no.: P37059
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... HSD17B2(3294)

Description

General description

HSD17B2 (Hydroxysteroid 17-β dehydrogenase 2) is a member of the short chain alcohol dehydrogenase superfamily expressed in non-steroidogenic human embryonic kidney cells.

Application

ANTI-HSD17B2 (CENTER) antibody produced in rabbit is suitable for flow cytometry (1:10-1:50), immunohistochemistry (1:50-1:100), and western blot: 1:250-1:500.

Biochem/physiol Actions

HSD17B2 (Hydroxysteroid 17-β dehydrogenase 2) is highly involved in the synthesis and metabolism of steroid hormones. It maintains the intracellular concentration of biologically active steroid hormones in a wide range of male and female human tissues. It catalyzes the interconversion of testosterone and androstenedione as well as estradiol and estrone through 17-β HSD activities. HSD17B2 also exhibits 20α-HSD activity toward 20α-dihydroprogesterone.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable