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P7754

5α-Pregnane-3,20-dione (allo)

progesterone metabolite

Synonym(s):

5α-Dihydroprogesterone, Allopregnane-3,20-dione

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About This Item

Empirical Formula (Hill Notation):
C21H32O2
CAS Number:
Molecular Weight:
316.48
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
209-297-3
MDL number:
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Quality Segment

form

powder

SMILES string

[H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](C(C)=O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CCC(=O)C2

InChI

1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14,16-19H,4-12H2,1-3H3/t14-,16-,17+,18-,19-,20-,21+/m0/s1

InChI key

XMRPGKVKISIQBV-BJMCWZGWSA-N

Biochem/physiol Actions

A high-level metabolite of progesterone in breast cancer tissue (but not normal breast tissue); promotes cell proliferation and detachment. Receptors appear only on the cell surface of MCF-7 breast cancer cells, not on nuclei where most other steroid receptors are located.

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This Item
P2016H5752PHR2905
description

progesterone metabolite

description

≥95%

description

≥95%

description

pharmaceutical secondary standard, certified reference material

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

300

form

powder

form

powder

form

powder

form

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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