Key Documents

View All Documentation

Dichloromethylenediphosphonic acid disodium salt

Name: Dichloromethylenediphosphonic acid disodium salt
Brand: SIGMA

osteoclastic activity inhibitor, powder

Synonym(s):

Cl₂MDP, Clodronate disodium, Clodronic acid disodium salt, DMDP

Select a Size

Change View

Size/SKU	Availability	Price

About This Item

Linear Formula:

CH₂O₆Cl₂Na₂P₂

CAS Number:

22560-50-5

Molecular Weight:

288.86

NACRES:

NA.77

PubChem Substance ID:

24278371

UNSPSC Code:

12352106

EC Number:

245-078-9

MDL number:

MFCD01632786

Form:

powder

Pricing and availability is not currently available.

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Dichloromethylenediphosphonic acid disodium salt,

form

powder

Quality Segment

300

solubility

water: 49.00-51.00 mg/mL, clear, colorless

storage temp.

room temp

SMILES string

[Na+].[Na+].OP([O-])(=O)C(Cl)(Cl)P(O)([O-])=O

InChI

1S/CH4Cl2O6P2.2Na/c2-1(3,10(4,5)6)11(7,8)9;;/h(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-2

InChI key

HJKBJIYDJLVSAO-UHFFFAOYSA-L

Gene Information

rat ... Man2a1(25478), Si(497756)

Description

Biochem/physiol Actions

Analog of pyrophosphate ion that inhibits the osteoclastic activity leading to bone resorption and osteoporosis. The compound is used in cancer research, especially in skeletal metastases and breast carcinoma. When entrapped in liposomes, it is used for macrophage-selective depletion (macrophage "suicide" technique), especially in spleen and liver. Found also to inhibit collagenase and matrix metalloproteinase1.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	D6899	E1644	B1125
Sigma-Aldrich D4434 Dichloromethylenediphosphonic acid disodium salt	Sigma-Aldrich D6899 Diclofenac sodium salt	Sigma-Aldrich E1644 Ethylenediaminetetraacetic acid disodium salt dihydrate	Sigma-Aldrich B1125 Bathocuproinedisulfonic acid disodium salt
description -	description -	description BioUltra, 98.5-101.5%	description for spectrophotometric det. of Cu, Fe
form powder	form powder	form powder	form powder
Quality Level 300	Quality Level 100	Quality Level 200	Quality Level 200
storage temp. room temp	storage temp. room temp	storage temp. room temp	storage temp. room temp
solubility water: 49.00-51.00 mg/mL, clear, colorless	solubility methanol: 50 mg/mL, clear, colorless to faint yellow or tan	solubility H₂O: 0.1 M, clear, colorless	solubility H₂O: 50 mg/mL
Gene Information rat ... Man2a1(25478), Si(497756)	Gene Information human ... PTGS1(5742), PTGS2(5743)	Gene Information -	Gene Information -

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.