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C8385

Potassium citrate tribasic monohydrate

≥98% (GC/titration)

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About This Item

Empirical Formula (Hill Notation):
C6H5K3O7 · H2O
CAS Number:
6100-05-6
Molecular Weight:
324.41
NACRES:
NA.25
PubChem Substance ID:
24893055
UNSPSC Code:
12161700
EC Number:
231-905-0
MDL number:
MFCD00150442

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InChI key

PJAHUDTUZRZBKM-UHFFFAOYSA-K

InChI

1S/C6H8O7.3K.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;1H2/q;3*+1;/p-3

SMILES string

O.[K+].[K+].[K+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

assay

≥98% (GC/titration)

form

powder

loss

3.0-6.0% loss on drying

pH

8.0-9.5

solubility

H2O: 100 mg/mL, clear, colorless

Quality Level

200

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This Item
2510760153P1722
Potassium citrate tribasic monohydrate ≥98% (GC/titration)

Sigma-Aldrich

C8385

Potassium citrate tribasic monohydrate

Potassium citrate tribasic monohydrate meets analytical specification of Ph. Eur., BP, FCC, E332, 99-100.5% (calc with ref. to anhyd. subst.)

Sigma-Aldrich

25107

Potassium citrate tribasic monohydrate

Potassium citrate tribasic monohydrate purum p.a., ≥99.0% (NT)

Sigma-Aldrich

60153

Potassium citrate tribasic monohydrate

Potassium citrate tribasic monohydrate meets USP testing specifications

Sigma-Aldrich

P1722

Potassium citrate tribasic monohydrate

assay

≥98% (GC/titration)

assay

99-100.5% (calc with ref. to anhyd. subst.)

assay

≥99.0% (NT)

assay

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder or crystals

form

liquid

form

crystals

pH

8.0-9.5

pH

7-9 (20 °C, 5%)

pH

7.5-9.0 (25 °C, 50 mg/mL in H2O)

pH

-

solubility

H2O: 100 mg/mL, clear, colorless

solubility

glycerol: soluble 1 gm in 2.5 ml, water: soluble 1 gm in 0.65 ml, alcohol: insoluble

solubility

H2O: 0.5 g/10 mL, clear, colorless

solubility

-

loss

3.0-6.0% loss on drying

loss

3-6 loss on drying, 180°C

loss

-

loss

-

Application

Potassium citrate tribasic monohydrate has been used in interconnected porous carbon nanosheets (IPCNs) synthesis.[1] It has also been used to study the use of clinical-grade Garcinia cambogia in Drosophila kidney stone models.[2]

Biochem/physiol Actions

Potassium citrate can be used to prepare citrate water that supports the survival of streptozotocin (STZ)-diabetic mice.[3] It might reduce the successive stone formation in calcium nephrolithiasis.[4] Potassium citrate serves as an activator for producing activated carbons.[5]

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000536583
0000536582
0000536582
0000536583
0000496733

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Clinical-grade Garcinia cambogia extract dissolves calcium oxalate crystals in Drosophila kidney stone models.
Fan, et al.
European Review for Medical and Pharmacological Sciences, 24, 6434-6445 (2021)
Protective Effect of Topiramate on Hyperglycemia-Induced Cerebral Oxidative Stress, Pericyte Loss and Learning Behavior in Diabetic Mice
Price TO, et al.
Biochemical and biophysical research communications, 1, 6-12 (2015)
The synergistic effect of oxygen-containing functional groups on CO 2 adsorption by the glucose-potassium citrate-derived activated carbon
Liu B, et al.
Royal Society of Chemistry Advances, 8(68), 38965-38973 (2018)
Mussel-inspired surface functionalization of porous carbon nanosheets using polydopamine and Fe 3+/tannic acid layers for high-performance electrochemical capacitors
Lee YA, et al.
Journal of Material Chemistry A, 5(48), 25368-25377 (2017)
Nancy S Krieger et al.
Journal of the American Society of Nephrology : JASN, 26(12), 3001-3008 (2015-04-10)
Potassium citrate is prescribed to decrease stone recurrence in patients with calcium nephrolithiasis. Citrate binds intestinal and urine calcium and increases urine pH. Citrate, metabolized to bicarbonate, should decrease calcium excretion by reducing bone resorption and increasing renal calcium reabsorption.
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