B7260

N_α-Benzoyl-L-arginine-7-amido-4-methylcoumarin hydrochloride

protease substrate, ≥99% (TLC), powder

• Synonym(s): Bz-Arg-AMC hydrochloride
• Empirical Formula (Hill Notation): C₂₃H₂₅N₅O₄ · HCl
• CAS Number: 83701-04-6
• Molecular Weight: 471.94
• UNSPSC Code: 12352204
• PubChem Substance ID: 24891979
• NACRES: NA.83
• MDL number: MFCD00039020

Properties

• Product Name: N_α-Benzoyl-L-arginine-7-amido-4-methylcoumarin hydrochloride, protease substrate
• Quality Segment: 200
• assay: ≥99% (TLC)
• form: powder
• solubility: DMSO:methanol (1:1): 20 mg/mL, clear, colorless
• storage temp.: −20°C
• SMILES string: Cl.CC1=CC(=O)Oc2cc(NC(=O)[C@H](CCCNC(N)=N)NC(=O)c3ccccc3)ccc12
• InChI: 1S/C23H25N5O4.ClH/c1-14-12-20(29)32-19-13-16(9-10-17(14)19)27-22(31)18(8-5-11-26-23(24)25)28-21(30)15-6-3-2-4-7-15;/h2-4,6-7,9-10,12-13,18H,5,8,11H2,1H3,(H,27,31)(H,28,30)(H4,24,25,26);1H/t18-;/m0./s1
• InChI key: XKAVYOJOHZLTDF-FERBBOLQSA-N

Description

General description

A sensitive fluorogenic substrate for papain and trypsin.

Application

Nα-Benzoyl-L-arginine-7-amido-4-methylcoumarin hydrochloride has been used:

• as a substrate for trypsin-like proteolysis of peptide in red blood cells
• as a substrate for midgut proteases of Pieris brassicae[1]
• as a substrate in screening serine protease activity of venom

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)