A8763
Albumin from human serum
lyophilized powder, essentially globulin free, ≥99% (agarose gel electrophoresis)
Synonym(s):
HSA
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About This Item
CAS Number:
UNSPSC Code:
12352202
eCl@ss:
42010201
EC Number:
274-272-6
NACRES:
NA.25
MDL number:
Biological source:
human
Assay:
≥99% (agarose gel electrophoresis)
Form:
lyophilized powder
Technique(s):
ELISA: suitable, tissue culture: suitable, western blot: suitable
Impurities:
HIV I and HIVII, HCV and HBsAg, tested negative
Concentration:
≤1% (Globulin)
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SMILES string
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
biological source
human
assay
≥99% (agarose gel electrophoresis)
form
lyophilized powder
mol wt
monomer calculated mol wt 66478 Da
concentration
≤1% (Globulin)
technique(s)
ELISA: suitable, tissue culture: suitable, western blot: suitable
impurities
HIV I and HIVII, HCV and HBsAg, tested negative
Quality Level
Gene Information
human ... ALB(213)
UniProt accession no.
storage temp.
2-8°C
solubility
H2O: soluble 20 mg/mL
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This Item | |||
|---|---|---|---|
| biological source human | biological source human | biological source - | biological source human |
| technique(s) ELISA: suitable, western blot: suitable, tissue culture: suitable | technique(s) cell culture | mammalian: suitable | technique(s) protein quantification: suitable | technique(s) cell culture | mammalian: suitable |
| assay ≥99% (agarose gel electrophoresis) | assay 90-100% protein basis (biuret) | assay ≥95% (SDS-PAGE) | assay ≥90% (agarose gel electrophoresis) |
| Quality Level 200 | Quality Level 200 | Quality Level - | Quality Level 300 |
| form lyophilized powder | form lyophilized powder | form lyophilized solid (Salt-free) | form lyophilized powder |
| impurities HIV I and HIVII, HCV and HBsAg, tested negative | impurities - | impurities - | impurities - |
General description
Albumin is the most copious protein in blood plasma. Liver produces human albumin.[1]
Application
Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia.[2] It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.[1]
Albumin was used to study albumin-induced apoptosis in proximal tubule cells. [3] It was also used in cell adhesion molecules and surface treatment studies.[4]
Albumin was used to study albumin-induced apoptosis in proximal tubule cells. [3] It was also used in cell adhesion molecules and surface treatment studies.[4]
Biochem/physiol Actions
Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.
Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin can also bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influences their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has varied effects on its physiological function.
Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.
Other Notes
View more information on human serum albumin.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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H K Parmentier et al.
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