A5806
9-Amino-6-chloro-2-methoxyacridine
suitable for fluorescence, ≥95%
Synonym(s):
ACMA
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About This Item
Empirical Formula (Hill Notation):
C14H11ClN2O
CAS Number:
Molecular Weight:
258.70
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
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Assay
≥95%
suitability
suitable for fluorescence
storage temp.
−20°C
SMILES string
COc1ccc2nc3cc(Cl)ccc3c(N)c2c1
InChI
1S/C14H11ClN2O/c1-18-9-3-5-12-11(7-9)14(16)10-4-2-8(15)6-13(10)17-12/h2-7H,1H3,(H2,16,17)
InChI key
IHHSSHCBRVYGJX-UHFFFAOYSA-N
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Yun Shi et al.
Bioconjugate chemistry, 16(2), 306-311 (2005-03-17)
Chirally pure phosphoramidite monomers bearing 9-amino-6-chloro-2-methoxyacridine were synthesized from D- or L-threoninol and omega-aminocarboxylic acid, and incorporated into oligonucleotides. These acridine-DNA conjugates formed stable duplexes with complementary RNA because of intercalation of the acridine to DNA/RNA heteroduplexes. The stability of
L Helfenbaum et al.
Journal of bioenergetics and biomembranes, 29(1), 71-80 (1997-02-01)
As part of the ongoing studies aimed at elucidating the mechanism of the energy conserving function of mitochondrial complex I, NADH: ubiquinone (Q) reductase, we have investigated how short-chain Q analogs activate the proton pumping function of this complex. Using
Sakurako Ono et al.
The Journal of biological chemistry, 279(32), 33409-33412 (2004-06-04)
In a rotary motor F1F0-ATP synthase, F0 works as a proton motor; the oligomer ring of F0c-subunits (c-ring) rotates relative to the F0ab2 domain as protons pass through F0 down the gradient. F0ab2 must exert dual functions during rotation, that
Ryuichi Ohgaki et al.
Biochimica et biophysica acta, 1712(2), 185-196 (2005-06-14)
The Saccharomyces cerevisiae Nha1p, a plasma membrane protein belonging to the monovalent cation/proton antiporter family, plays a key role in the salt tolerance and pH regulation of cells. We examined the molecular function of Nha1p by using secretory vesicles isolated
William B Davis et al.
Journal of the American Chemical Society, 124(11), 2422-2423 (2002-03-14)
The recent investigation of the apparently anomalous attenuation factor (beta > 1.5 A(-1)) for photoinduced hole injection into DNA duplexes modified by protonated 9-amino-6-chloro-2-methoxyacridine (X+) led to the conclusion that in addition to the electronic couplings, the activation energy must
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