Key Documents

View All Documentation

AS 604850

Name: AS 604850
Brand: SIGMA

≥98% (HPLC), solid

Synonym(s):

5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione, PI3Kγ inhibitor

Select a Size

Change View

Size/SKU	Availability	Price

About This Item

Empirical Formula (Hill Notation):

C₁₁H₅F₂NO₄S

CAS Number:

648449-76-7

Molecular Weight:

285.22

NACRES:

NA.77

PubChem Substance ID:

24724381

UNSPSC Code:

12352200

MDL number:

MFCD19705528

Assay:

≥98% (HPLC)

Form:

solid

Pricing and availability is not currently available.

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Segment

100

assay

≥98% (HPLC)

form

solid

color

off-white

solubility

DMSO: >10 mg/mL, H₂O: <2 mg/mL

shipped in

wet ice

storage temp.

2-8°C

SMILES string

FC1(F)Oc2ccc(cc2O1)\C=C3/SC(=O)NC3=O

InChI

1S/C11H5F2NO4S/c12-11(13)17-6-2-1-5(3-7(6)18-11)4-8-9(15)14-10(16)19-8/h1-4H,(H,14,15,16)/b8-4-

InChI key

SRLVNYDXMUGOFI-YWEYNIOJSA-N

Description

Biochem/physiol Actions

AS 604850 is a selective PI3Kγ inhibitor

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphoinositide Kinases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	SML1731	526524	528106
Sigma-Aldrich A0231 AS 604850	Sigma-Aldrich SML1731 A64 trifluoroacetate	Sigma-Aldrich 526524 PIM1/2 Kinase Inhibitor VI	Sigma-Aldrich 528106 PI 3-Kγ Inhibitor
description ≥98% (HPLC), solid	description ≥98% (HPLC)	description The PIM1/2 Kinase Inhibitor VI, also referenced under CAS 587852-28-6, controls the biological activity of PIM1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.	description The PI 3-Kγ Inhibitor, also referenced under CAS 648450-29-7, controls the biological activity of PI 3-Kγ. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥95% (HPLC)	assay ≥90% (HPLC)
form solid	form powder	form solid	form solid
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
solubility H₂O: <2 mg/mL, DMSO: >10 mg/mL	solubility H₂O: 10 mg/mL, clear	solubility DMSO: 25 mg/mL	solubility DMSO: 2.5 mg/mL
color off-white	color white to beige	color yellow	color pink

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.