137274

MES sodium salt

EMPROVE^® EVOLVE

• Synonym(s): MES sodium salt, 2-(N-Morpholino)ethanesulfonic acid sodium salt, 4-Morpholineethanesulfonic acid sodium salt
• Empirical Formula (Hill Notation): C₆H₁₂NNaO₄S
• CAS Number: 71119-23-8
• Molecular Weight: 217.22
• UNSPSC Code: 12161700
• Beilstein/REAXYS Number: 3765682
• MDL number: MFCD00065473

Properties

• biological source: synthetic
• Quality Segment: 400
• product line: EMPROVE^® EVOLVE
• form: powder
• technique(s): cell culture | mammalian: suitable, pH adjustment: suitable
• impurities: Endotoxin and microbial; tested
• useful pH range: 5.5-6.7
• pKa: 6.1
• suitability: suitable for manufacturing use
• foreign activity: Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
• storage temp.: 2-30°C
• SMILES string: [Na+].[O-]S(=O)(=O)CCN1CCOCC1
• InChI: 1S/C6H13NO4S.Na/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);/q;+1/p-1
• InChI key: IRHWMYKYLWNHTL-UHFFFAOYSA-M

Description

Application

MES Sodium is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES Sodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.MES Sodium is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream) and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• WGK: WGK 1