The substance is soluble in water (4 mg/l at 25°C), alcohol (38.2 mg/ml), ether (71.4 mg/ml), chloroform, and acetonitrile.
PHR1690
Disulfiram
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
Tetraethylthiuram disulfide, Bis(diethylthiocarbamoyl) disulfide, Bis(diethylthiocarbamyl) disulfide, Disulfiram, TETD
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Linear Formula:
(C2H5)2NCSS2CSN(C2H5)2
CAS Number:
Molecular Weight:
296.54
Beilstein:
1712560
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.
Recommended Products
grade
certified reference material
pharmaceutical secondary standard
Quality Level
Agency
traceable to BP 132
traceable to Ph. Eur. D2950000
traceable to USP 1224008
API family
disulfiram
CofA
current certificate can be downloaded
packaging
pkg of 1 g
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
69-71 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
CCN(CC)C(=S)SSC(=S)N(CC)CC
InChI
1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3
InChI key
AUZONCFQVSMFAP-UHFFFAOYSA-N
Gene Information
human ... ALDH2(217)
Looking for similar products? Visit Product Comparison Guide
General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Disulfiram is clinically used in the treatment of chronic alcoholism.[1]
Disulfiram is clinically used in the treatment of chronic alcoholism.[1]
Application
Disulfiram may be used as a pharmaceutical reference standard for the determination of the analyte in biological fluids[1][2] and pharmaceutical formulations[3] by high performance liquid chromatography and spectrophotometry, respectively.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Alcohol dehydrogenase inhibitor.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAC2079 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
Recommended products
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1 - STOT RE 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Spectrophotometric determination of methimazole, D-penicillamine, captopril, and disulfiram in pure form and drug formulations
Skowron M and Ciesielski W
Journal of Analytical Chemistry, 66(8), 714-719 (2011)
Determination of disulfiram and metabolites from biological fluids by high-performance liquid chromatography
Jensen JC, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 181(3-4), 407-416 (1980)
Simultaneous determination of disulfiram and two of its dithiocarbamate metabolites in human plasma by reversed-phase liquid chromatography
Masso PD, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 224(3), 457-464 (1981)
-
What is the solubility of the product Disulfiram (PHR1690) in water and other solvents?
1 answer-
Helpful?
-
-
Is this product soluble? what is it storage temperature after it has dissolved. Is there any manual for that?
1 answer-
This product is soluble in water at approximately 4 ug/mL at 25° C, alcohol at 38.2 mg/ml, ether at 71.4 mg/ml, as well as chloroform, and acetonitrile. Solutions may require rapid stirring, sonication or gentle warming (in a 45-60°C water bath) in order to fully dissolve. Issues concerning product stability, particularly in solution, have rarely been reported. Stock solutions may be stored aliquoted in tightly sealed vials at -20°C or below for up to 1 month.
Helpful?
-
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
