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H9645

Supelco

p-Hydroxymethamphetamine

analytical standard, for drug analysis

Synonym(s):

Pholderin

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About This Item

Empirical Formula (Hill Notation):
C10H15NO
CAS Number:
370-14-9
Molecular Weight:
165.23
EC Number:
206-725-0
MDL number:
MFCD00178702
UNSPSC Code:
41116107
PubChem Substance ID:
329815268
NACRES:
NA.24
Pricing and availability is not currently available.

grade

analytical standard, for drug analysis

Quality Level

200

Assay

≥98% (TLC)

drug control

Home Office Schedule 1; regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

−20°C

SMILES string

CNC(C)Cc1ccc(O)cc1

InChI

1S/C10H15NO/c1-8(11-2)7-9-3-5-10(12)6-4-9/h3-6,8,11-12H,7H2,1-2H3

InChI key

SBUQZKJEOOQSBV-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

A metabolite of methamphetamine; sympathomimetic

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000415093
0000415093
0000148527
0000148527
0000130469

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Shimosato, K., et al.
Journal of Chromatographic Science, 377, 279-279 (1986)
T Yamamoto et al.
Journal of analytical toxicology, 13(2), 117-119 (1989-03-01)
A sensitive and specific gas chromatography/mass spectrometry (GC/MS) method has been developed for the simultaneous analysis of methampthetamine and its metabolites (amphetamine, p-hydroxymethamphetamine, and p-hydroxyamphetamine) in monkey urine. The method has been applied to the analysis of urine samples from
Noriyuki Kato et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 21(9), 1117-1119 (2005-12-21)
A highly-sensitive analytical method for the detection of p-hydroxymethamphetamine (pOHMA) in urine is presented. The proposed method combines liquid-liquid extraction with acetonitrile and solid-phase extraction by thin-layer chromatography (TLC) with oxidation using potassium hexacyanoferrate(III) and sodium hydroxide to detect the
Akihiro Miki et al.
Journal of analytical toxicology, 27(2), 95-102 (2003-04-03)
An automated column-switching liquid chromatographic-electrospray ionization-mass spectrometric (LC-ESI-MS) method has been established for the determination of methamphetamine (MA) and its metabolites, amphetamine (AP), and p-hydroxymethamphetamine (p-OH-MA) in hair. The combination of an N-vinylacetamide-containing hydrophilic polymer online extraction column, an SCX
N Shima et al.
Xenobiotica; the fate of foreign compounds in biological systems, 36(2-3), 259-267 (2006-05-17)
The urinary concentrations of the main metabolites of methamphetamine (MA), specifically p-hydroxymethamphetamine-sulfate (p-OHMA-Sul) and p-hydroxymethamphetamine-glucuronide (p-OHMA-Glu), were directly measured in MA users and rats using an optimized LC-ESI MS method. The concentrations of the two conjugates in 50 MA human
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