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F6270

Supelco

Fipexide hydrochloride

analytical standard

Synonym(s):

1-(2-[4-Chlorophenoxy]acetyl)-4-(3,4-methylenedioxybenzyl)piperazine

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About This Item

Empirical Formula (Hill Notation):
C20H21ClN2O4 · HCl
CAS Number:
34161-24-5
Molecular Weight:
425.31
EC Number:
251-857-4
MDL number:
MFCD00133323
UNSPSC Code:
41116107
PubChem Substance ID:
329799752
NACRES:
NA.24
Pricing and availability is not currently available.

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.Clc1ccc(OCC(=O)N2CCN(CC2)Cc3ccc4OCOc4c3)cc1

InChI

1S/C20H21ClN2O4.ClH/c21-16-2-4-17(5-3-16)25-13-20(24)23-9-7-22(8-10-23)12-15-1-6-18-19(11-15)27-14-26-18;/h1-6,11H,7-10,12-14H2;1H

InChI key

MVOWQBJZZKOQNU-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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André Leblanc et al.
Rapid communications in mass spectrometry : RCM, 24(9), 1241-1250 (2010-04-15)
Drug bioactivation leading to the formation of reactive species capable of covalent binding to proteins represents an important cause of drug-induced toxicity. Reactive metabolite detection using in vitro microsomal incubations is a crucial step in assessing potential toxicity of pharmaceutical
[Fever after taking fipexide hydrochloride].
C Guy et al.
Presse medicale (Paris, France : 1983), 18(21), 1076-1076 (1989-05-27)
R Bompani et al.
Current medical research and opinion, 10(2), 99-106 (1986-01-01)
Forty geriatric in-patients with severe cognition disorders were randomly allocated to treatment with either 600 mg fipexide daily or placebo over a period of 3 weeks. Before and after treatment, the symptoms of cognitive performance (disorders of memory and attention
Roland F Staack et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 804(2), 337-343 (2004-04-15)
Qualitative studies are described on the metabolism and the toxicological analysis of the nootropic fipexide (FIP) in rat urine using gas chromatography-mass spectrometry (GC-MS). FIP was extensively metabolized to 1-(3,4-methylenedioxybenzyl)piperazine (MDBP), 4-chlorophenoxyacetic acid, 1-[2-(4-chlorophenoxy)acetyl]piperazine, N-(4-hydroxy-3-methoxy-benzyl)piperazine, piperazine, N-(3,4-methylenedioxybenzyl)ethylenediamine, and N-[2-(4-chlorophenoxy)acetyl]ethylenediamine. The
M B Lazarova-Bakarova et al.
Methods and findings in experimental and clinical pharmacology, 11(4), 235-239 (1989-04-01)
The effects of four nootropic drugs (piracetam, aniracetam, meclofenoxate and fipexide) on cognitive functions impaired by the antihypertensive drug clonidine were investigated in albino rats. The changes in learning and memory were studied by two-way active avoidance with punishment reinforcement
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