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BCR265

Dibenzo[a,e]fluoranthene

BCR®, certified reference material

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About This Item

Empirical Formula (Hill Notation):
C24H14
CAS Number:
5385-75-1
Molecular Weight:
302.37
Beilstein:
2120920
MDL number:
MFCD00215892
UNSPSC Code:
41116107
PubChem Substance ID:
329773799
NACRES:
NA.24
Pricing and availability is not currently available.

grade

certified reference material

Agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

SMILES string

c1ccc-2c(c1)-c3cc4ccccc4c5cc6ccccc6c-2c35

InChI

1S/C24H14/c1-3-9-17-15(7-1)13-22-19-11-5-6-12-20(19)23-18-10-4-2-8-16(18)14-21(17)24(22)23/h1-14H

InChI key

JHOWUOKQHJHGMU-UHFFFAOYSA-N

Analysis Note

For more information please see:
BCR265

Legal Information

BCR is a registered trademark of European Commission

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H351

Precautionary Statements

P201 - P308 + P313

Hazard Classifications

Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Metabolic activation of dibenzo(a,e)fluoranthene, a nonalternant carcinogenic polycyclic hydrocarbon, in liver homogenates.
O Perin-Roussel et al.
Cancer research, 40(5), 1742-1749 (1980-05-01)
O Perin-Roussel et al.
Cancer letters, 36(2), 169-180 (1987-08-01)
The production by dibenzo[a,e]fluoranthene (DBF) of DNA-protein cross-links in cultured mouse fibroblasts is probably mediated by the activation of proximate metabolites of DBF and not by the DBF molecule itself. In order to test this hypothesis, several agents that enhance
F Zajdela et al.
Carcinogenesis, 8(3), 461-464 (1987-03-01)
Dibenzofluoranthene-12,13-dihydrodiol (DBF-12,13-DHD) is six times more mutagenic in Salmonella TA100 than dibenzofluoranthene-3,4-dihydrodiol (DBF-3,4-DHD). However, these two major dibenzo[a,e]fluoranthene (DBF) proximate metabolites, which are immediate precursors of the corresponding diolepoxides, showed on an equimolar basis nearly identical initiation activities on mouse
S Saguem et al.
Carcinogenesis, 4(7), 827-835 (1983-01-01)
The metabolism of the polycyclic hydrocarbon dibenzo[a,e]fluoranthene (DBF) has been investigated. Two new primary metabolites have been identified by proton n.m.r. as the trans diaxial dihydrodiols of the bay and of the pseudo bay regions of DBF. In addition, twelve
O Périn-Roussel et al.
Carcinogenesis, 11(2), 301-306 (1990-02-01)
The formation of DNA adducts was investigated in mouse fibroblasts treated with dibenzo[a,e]fluoranthene (DBF), using the nuclease P1 modification of the 32P-post-labeling method. In order to separate the poorly soluble, bulky DNA adducts of this potent sarcomogenic, six-ring polycyclic aromatic
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