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81440

Sigma-Aldrich

Polyvinylpyrrolidone

Polyvinylpyrrolidone

K 90

Synonym(s):

PVP, Polyvidone, Povidone

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About This Item

Linear Formula:
(C6H9NO)n
CAS Number:
9003-39-8
MDL number:
MFCD00149016
UNSPSC Code:
12162002
PubChem Substance ID:
24887621
NACRES:
NA.23
Pricing and availability is not currently available.

Quality Level

200

form

powder or crystals (or flakes)

SMILES string

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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Application

Polyvinylpyrrolidone (PVP),also known as K90 is a water soluble polymer with good bio-stability. It is chemically stable, has low toxicity and is biocompatible. Hence, it is useful in a variety of applications such as cosmetics, tissue engineering, and biomedical engineering.[1][2][3]

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL8451
BCCL6242
BCCL6572
BCCH5580
BCCK1201

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Development of poly (l-lactic acid) hollow fiber membranes for artificial vasculature in tissue engineering scaffolds
Bettahalli NMS, et al.
Journal of Membrane Science , 371(1-2), 117-126 (2011)
A high flux ultrafiltration membrane spun from PSU/PVP (K90)/DMF/1, 2-propanediol
Qin J, et al.
Journal of Membrane Science , 211(1), 139-147 (2003)
Mass and controlled fabrication of aligned PVP fibers for matrix type antibiotic drug delivery systems
Wang L, et al.
Chemical Engineering Journal, 307, 661-669 (2017)
Aaron R Jex et al.
Journal of clinical microbiology, 46(7), 2252-2262 (2008-05-02)
In the present study, we analyzed genetic variation in Cryptosporidium species from humans (n = 62) with clinical cryptosporidiosis in South Australia. Sequence variation was assessed in regions within the small subunit of nuclear rRNA (p-SSU), the 70-kDa heat shock
Nicole M Sanders et al.
American journal of physiology. Endocrinology and metabolism, 294(5), E853-E860 (2008-03-13)
Selective serotonin reuptake inhibitors (SSRIs) are widely prescribed for patients with comorbid diabetes and depression. Clinical case studies in diabetic patients, however, suggest that SSRI therapy may exacerbate hypoglycemia. We hypothesized that SSRIs might increase the risk of hypoglycemia by
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Questions

1–4 of 4 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Do you have any information about the chemical stability of 10% PVP solution in 0,9% NaCl. Storage temperature 5°C.

    1 answer

    1. The stability of this product in solution has not been determined. However, product 81430 is a 45% solution of the PVP K60 in water. This product is not assigned an expiration or retest date, but includes a warranty of 1 year from the date of shipment. A 10% solution of the PVP K90 in normal saline may offer a similar shelf-life expectation.

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  4. What is the molecular weight of the polymer?

    1 answer

    1. The molecular weight of this compound is approximately 360 kDa.

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