Key Documents

View All Documentation

Caspase-3 Substrate VII, Fluorogenic

Name: Caspase-3 Substrate VII, Fluorogenic
Brand: MM

Fluorogenic caspase-3 substrate.

Synonym(s):

Caspase-3 Substrate VII, Fluorogenic, Ac-DEVD-AFC

Select a Size

Change View

Size/SKU	Availability	Price

About This Item

Empirical Formula (Hill Notation):

C₃₀H₃₄F₃N₅O₁₃

Molecular Weight:

729.61

NACRES:

NA.77

UNSPSC Code:

12352200

Assay:

≥95% (HPLC)

Form:

lyophilized solid

Storage condition:

OK to freeze, desiccated, protect from light

Pricing and availability is not currently available.

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Segment

100

assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated, protect from light

color

white

solubility

DMSO: 5 mg/mL

fluorescence

λ_ex ~400 nm, λ_em ~505 nm

shipped in

ambient

storage temp.

−20°C

Description

General description

Fluorogenic caspase-3 substrate (excitation maximum: ~400 nm; emission maximum: ~505 nm). Also acts as a substrate for granzyme B-processed ICE-LAP3, caspase-6, caspase-7, caspase-8, and caspase-10.

Fluorogenic caspase-3 substrate. Also acts as a substrate for granzyme B-processed caspase-6, caspase-7, caspase-8, and caspase-10.

Biochem/physiol Actions

Reversible: no

Cell permeable: no

Primary Target
Fluorogenic caspase-3 substrate

Product does not compete with ATP.

Preparation Note

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Ac-Asp-Glu-Val-Asp-AFC

Keramaris, E., et al. 2000. Mol. Cell Neurosci. 15, 368.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	235425	218739	264150
Sigma-Aldrich 264151 Caspase-3 Substrate VII, Fluorogenic	Sigma-Aldrich 235425 Caspase-3 Substrate II, Fluorogenic	Sigma-Aldrich 218739 Caspase-1 Substrate X, Fluorogenic	Sigma-Aldrich 264150 Caspase-3 Substrate IV, Fluorogenic
description Fluorogenic caspase-3 substrate.	description Fluorogenic caspase-3 substrate.	description A fluorogenic substrate for detecting caspase-1 (ICE), caspase-4, and caspase-5 activity.	description Fluorogenic caspase-3 substrate.
assay ≥95% (HPLC)	assay ≥95% (HPLC)	assay ≥95% (HPLC)	assay ≥95% (HPLC)
form lyophilized solid	form solid	form lyophilized	form solid
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
solubility DMSO: 5 mg/mL	solubility DMSO: 10 mM	solubility DMSO: 5 mg/mL	solubility DMSO: 10 mg/mL

Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.