The solubility of this USP standard has not been determined. Various sources note that this material is soluble at 0.885 mg/mL in water. In addition, PBS at pH 3.2 and 0.01 M HCl are listed, with no concentration reported. Please see the links below to review additional information that may be helpful:
https://pubs.acs.org/doi/10.1021/acs.jced.0c00047#
https://go.drugbank.com/drugs/DB00402
https://patents.google.com/patent/EP1997482A1/en
1255850
USP
Eszopiclone
United States Pharmacopeia (USP) Reference Standard
동의어(들):
(+)-Eszopiclone, (+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate, (S)-Zopiclone
About This Item
Grade
pharmaceutical primary standard
API family
eszopiclone
제조업체/상표
USP
약물 제어
USDEA Schedule IV
응용 분야
pharmaceutical (small molecule)
형식
neat
SMILES string
Clc1cnc(cc1)N2[C@H](c4nccnc4C2=O)OC(=O)N3CCN(CC3)C
InChI
1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3/t16-/m0/s1
InChI key
GBBSUAFBMRNDJC-INIZCTEOSA-N
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일반 설명
For further information and support please go to the website of the issuing Pharmacopoeia.
애플리케이션
- Eszopiclone Tablets
분석 메모
기타 정보
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 2 - STOT SE 3
표적 기관
Central nervous system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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Hi. What is the solubility of Eszopiclone in water and PBS?
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