G1007465

HPLC Analysis of Alfuzosin and Related Substances on Chromolith^® HighResolution RP-18 endcapped

application for HPLC

속성

• 기술: HPLC: suitable
• 검사 파라미터: sample preparation: Dissolve 40.0 mg of the sample in 100 mL of mobile phase. 0.4 mg/mL (400 ppm) of USP Alfuzosin System Suitability Mixture RS in Mobile phase; column: Chromolith^® HighResolution RP-18 endcapped, 150 x 4.6 mm (1.52023.0001); mobile phase: [A] 5 ml of perchloric acid in 900 mL Milli-Q water. Adjust pH to 3.5 with 2M NaOH. Diluter to 1000 mL with water; [B] acetonitrile; [C] THF; (80:20:1, A:B:C); flow rate: 1 mL/min; pressure: 994 psi (69 Bar); column temp.: 25 °C; detector: 254 nm cell: 10 μL; injection: 10 μL; sample: 0.40 μg/mL of Alfuzosin Hydrochloride in Mobile phase from the Sample solution
• 적합성: application for HPLC
• 응용 분야: pharmaceutical (small molecule)

설명

법적 정보

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany

분석물

Deacylated Alfuzosin
Alfuzosin
Furamide analog